: A potential prognostic biomarker of colorectal cancer.

Colorectal cancer (CRC) is the third most common malignancy worldwide with the second highest mortality rate. Although multidisciplinary cooperative therapies are helpful for improving the survival of CRC patients, the prognosis remains poor. Therefore, it is imperative to seek new biomarkers for the development of individualized treatment for each CRC patient.

Epidemiological characteristics of acute disseminated encephalomyelitis in Nanchang, China: a retrospective study.

Background: Acute disseminated encephalomyelitis (ADEM) is an autoimmune disease that typically follows a monophasic course and may affect any age group. The precise population-based incidence of ADEM is still unknown in most countries. In China, there is no ADEM surveillance system.

[Analysis of molecular subtypes and microflora structure of Neisseria meningitidis strains isolated in Jiangxi province].

Objective: To study the molecular subtypes and microflora structure of Neisseria meningitidis (Nm) strains isolated in Jiangxi province.

Methods: A total of 123 Nm strains separately isolated from patients, close contacts and health people in 1976-1987 and 2005-2008 were investigated by multilocus sequence typing (MLST) and PorA subtyping, to test the characteristics of gene Nm and sequence porA. Minimum spanning tree was constructed by using BioNumerics software based on data of MLST; and the microflora structure was then analyzed.

[Molecular typing on Leptospira interrogans isolates from Jiangxi province, by pulsed-field gel electrophoresis].

Objective: To perform a molecular epidemiological investigation on the types of Leptospira interrogans isolates from leptospirosis patients and animal hosts in Jiangxi province, using a pulsed-field gel electrophoresis (PFGE).

Methods: The extracted chromosomal DNA from leptospiral isolates were digested with restriction endonuclease Not I and the DNA segments were separated by using PFGE. By BiOnurerics V4.

[Evaluation on effectiveness of training for the national expanded program on immunization].

Objective: To evaluate the effectiveness of training for the national expanded program on immunization.

Methods: 384 trainees were selected random. A questionnaire was developed and distributed to the trainees before and after training.

[A systematic review on the protective efficacy of BCG against children tuberculosis meningitis and millet tuberculosis].

Objective: To Understand the protective efficacy of Bacillus Calmette Guerin (BCG) vacciation against children tuberculosis meningitis and millet tuberculosis, to provide the data to improve immune tactics of BCG.

Methods: A search CHKD full text database (1979-2007) and CHKD meeting paper database (1999-2008) and WANGFANG database (1982-2007), with BCG, tuberculosis meningitis, millet tuberculosis, then to analyze information from qualified literatures.

Results: 28 paper were involved.