[Treatment of advanced metastatic breast cancer with exemestane, a multicenter randomized controlled study of 195 cases].

Objective: To observe the efficacy of exemestane for postmenopausal advanced metastatic breast cancer, and to assess its side effects.

Methods: A randomized, double-blind, and parallel controlled study was conducted among 195 patients with postmenopausal advanced metastatic breast cancer from December 2001 to June 2002. Except for the 4 cases who were lost to follow-up, the remaining 191 patients were divided into two groups: study group (n = 96, treated with exemestane capsule 25 mg and one model tablet of letrozole orally q.