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Publications by authors named "Chang-an Geng"

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Synopsis of recent research by authors named "Chang-an Geng"

  • - Chang-An Geng's recent research primarily focuses on the pharmacological properties of natural compounds, particularly those derived from various plants, aimed at treating conditions related to diabetes, obesity, and cancer.
  • - Significant findings include the isolation of numerous new compounds with therapeutic potential, such as labdane diterpenoids from Alpinia galanga that function as GLP-1 secretagogues and beta-site amyloid protein precursor cleaving enzyme 1 (BACE1) inhibitors from Alpinia oxyphylla effective for treating cognitive disorders linked to type 2 diabetes.
  • - Additionally, Geng's work explores the modulation of cellular pathways, such as the targeting of estrogen-related receptor α (ESRRA) to enhance bone health, as well as the inhibitory effects of specific compounds on immune responses, showcasing an integrative approach to address multifaceted health issues using biochemically active natural products.

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