Publications by authors named "Chang-Xuan Zhang"
Org Biomol Chem
March 2023
Article Synopsis
- The study focuses on a method for the enantioselective conjugate addition of malonates to α,β-unsaturated aldehydes, using 4-oxalocrotonate tautomerase as a catalyst.
- The process demonstrated high conversion rates, strong enantioselectivity, and good yields for various substrates.
- Additionally, the researchers successfully synthesized the antidepressant (+)-femoxetine using this reaction combined with an enzymatic reductive amination.
