Exploring diabetes through the lens of AI and computer vision: Methods and future prospects.

Early diagnosis and timely initiation of treatment plans for diabetes are crucial for ensuring individuals' well-being. Emerging technologies like artificial intelligence (AI) and computer vision are highly regarded for their ability to enhance the accessibility of large datasets for dynamic training and deliver efficient real-time intelligent technologies and predictable models. The application of AI and computer vision techniques to enhance the analysis of clinical data is referred to as eHealth solutions that employ advanced approaches to aid medical applications.

A Stool DNA-Based SDC2 Methylation Test for the Early Detection of Colorectal Cancer in an Asymptomatic, High-Risk Population: A Multicenter Prospective Randomized Trial.

Introduction: Noninvasive stool DNA-based methylation testing has emerged as an effective strategy for the early colorectal cancer (CRC) detection. Syndecan-2 (SDC2) methylation frequently occurs in all stages of CRC; therefore, the aim of this study was to evaluate the clinical performance of a stool DNA-based SDC2 methylation test for detecting CRC in asymptomatic or high-risk CRC populations.

Methods: This multicenter prospective study was conducted to determine the clinical performance of the SDC2 methylation test on stool DNA using real-time polymerase chain reaction.

Exploring the Potential of Linear π-Bridge Structures in a D-π-A Organic Photosensitizer for Improved Open-Circuit Voltage.

We present the design, synthesis, and evaluation of novel metal-free photosensitizers based on D-π-A structures featuring tri-arylamine as an electron donor, cyanoacrylic acid as an anchoring group, and substituted derivative π-bridges including 9,9-dimethyl-9H-fluorene, benzo[]thiophene, or naphtho [1,2-:4,3-']dithiophene. The aim of the current research is to unravel the relationship between chemical structure and photovoltaic performance in solar cell applications by investigating the properties of these organic sensitizers. The newly developed photosensitizers displayed variations in HOMO-LUMO energy gaps and photovoltaic performances due to their distinct π-bridge structures and exhibited diverse spectral responses ranging from 343 to 490 nm.

γ-Mangosteen, an autophagy enhancer, prevents skin-aging via activating KEAP1/NRF2 signaling and downregulating MAPKs/AP-1/NF-κB-mediated MMPs.

Background: Mangosteens, a naturally occurring xanthones, found abundantly in mangosteen fruits. The anti-skin aging potential of γ-mangosteen (GM) remains unexplored; therefore, we investigated the UVB-induced anti-skin aging of GM via activation of autophagy.

Hypothesis: We hypothesized that GM exerts antioxidant and anti-aging capabilities both in vitro and in vivo through activation of autophagy as well as control of KEAP1/NRF2 signaling and MAPKs/AP-1/NF-κB-mediated MMPs pathways.

General framework for quantifying dissipation pathways in open quantum systems. I. Theoretical formulation.

We present a general and practical theoretical framework to investigate how energy is dissipated in open quantum system dynamics. This is performed by quantifying the contributions of individual bath components to the overall dissipation of the system. The framework is based on the Nakajima-Zwanzig projection operator technique, which allows us to express the rate of energy dissipation into a specific bath degree of freedom by using traces of operator products.

General framework for quantifying dissipation pathways in open quantum systems. II. Numerical validation and the role of non-Markovianity.

In the previous paper [C. W. Kim and I.

Plastic Wound Protector vs Surgical Gauze for Surgical Site Infection Reduction in Open GI Surgery: A Randomized Clinical Trial.

Importance: Surgical site infections (SSIs) are prevalent hospital-acquired infections with significant patient impacts and global health care burdens. The World Health Organization recommends using wound protector devices in abdominal surgery as a preventive measure to lower the risk of SSIs despite limited evidence.

Objective: To examine the efficacy of a dual-ring, plastic wound protector in lowering the SSI rate in open gastrointestinal (GI) surgery irrespective of intra-abdominal contamination levels.

Musculoskeletal Pain, Physical Activity, Muscle Mass, and Mortality in Older Adults: Results from the Korean Longitudinal Study on Health and Aging (KLoSHA).

Musculoskeletal (MSK) pain significantly impacts physical activity and quality of life in older adults, potentially influencing mortality. This study explored the relationship between MSK pain, physical activity, muscle mass, and mortality among older adults. We studied 1000 participants in the Korean Longitudinal Study on Health and Aging (KLoSHA), a prospective, population-based cohort study of people aged 65 years or older.

Exploring the source of ammonia generation in electrochemical nitrogen reduction using niobium nitride.

In this study, niobium nitride (NbN) is prepared the urea-glass route by annealing a mixture of NbCl and urea at 650 °C under a flow of N, and is used as a catalyst for the electrochemical nitrogen reduction reaction (NRR). The as-prepared NbN exhibits a maximum production rate of 5.46 × 10 mol s cm at -0.

Mapping electronic decoherence pathways in molecules.

Establishing the fundamental chemical principles that govern molecular electronic quantum decoherence has remained an outstanding challenge. Fundamental questions such as how solvent and intramolecular vibrations or chemical functionalization contribute to the decoherence remain unanswered and are beyond the reach of state-of-the-art theoretical and experimental approaches. Here we address this challenge by developing a strategy to isolate electronic decoherence pathways for molecular chromophores immersed in condensed phase environments that enables elucidating how electronic quantum coherence is lost.

Coxiella burnetii infection in a patient with tick bite.

Introduction: We report the case of a 60-year-old male who was hospitalized with fever, headache, fatigue, nausea, and myalgia for six days.

Methodology: Polymerase chain reactions (PCR) were performed on patient blood samples, and four ticks were collected from the area the patient mowed. Indirect immunofluorescence assays (IFAs) were performed on serum samples to detect specific antibodies.

Borderline Malignant Sebaceoma of the Auricle: A Case Report.

Unlabelled: Sebaceoma is a rare benign tumor arising from the sebaceous gland of the skin. Sebaceoma often occurs on the head and neck but rarely on the ears. We present the case of a 78-year-old female patient with a two-year history of a protruding mass in her left ear.

Public effect of the 2022 Colorectal Cancer Awareness Campaign delivered through a metaverse platform.

Purpose: The Korean Society of Coloproctology has been conducting Colorectal Cancer Awareness Campaign, also known as the Gold Ribbon Campaign, every September since 2007. The 2022 campaign was held through a metaverse platform targeting the younger age group under the slogan of raising awareness of early-onset colorectal cancer (CRC). This study aimed to analyze the impact of the 2022 campaign on a metaverse platform.

Correction to "Surface Thermal Behavior and RT CO Gas Sensing Application of Oligoacenaphthylene with -Hydroxyphenylacetic Acid Composite".

[This corrects the article DOI: 10.1021/acsomega.2c03897.

High Serum Levels of IL-6 Predict Poor Responses in Patients Treated with Pembrolizumab plus Axitinib for Advanced Renal Cell Carcinoma.

Renal cell carcinoma (RCC) is the most common type of kidney malignancy worldwide with Pembrolizumab and axitinib treatment (Pembro/Axi) amongst the most effective first-line immunotherapies for advanced RCC. However, it remains difficult to predict treatment response and early resistance. Therefore, we evaluated whether baseline serum interleukin-6 (IL-6) could be a predictive biomarker.

Defectronics based photoelectrochemical properties of Cu ion doped hematite thin film.

The concentration of guest elements (dopants) into host materials play an important role in changing their intrinsic electrical and optical properties. The existence of hetero-element induce defect in crystal structure, affecting conductivity. In the current work, we report Cu ion into hematite in the defectronics point of view and their photoelectrochemical properties.

Surface Thermal Behavior and RT CO Gas Sensing Application of an Oligoacenaphthylene with -Hydroxyphenylacetic Acid Composite.

The current work describes room-temperature gas sensing performances using an oligoacenaphthylene (OAN)/-hydroxyphenylacetic acid (-HPA) composite. Based on inverse gas chromatography (IGC), the London dispersive surface energy γ is calculated by using 14 representative models. Even when the γ values of both OAN and the OAN/-HPA composite are decreased as the temperature increases, the surface of OAN shows a higher value than that of the composite.

Laparoscopic repair of perforated peptic ulcer: a multicenter, propensity score matching analysis.

Background: Perforated peptic ulcer (PPU) is a common emergency condition requiring surgery using laparoscopy or open repair of the perforated site. The aim of this study was to assess the role of laparoscopic surgery (LS) based on the safety and efficacy for PPU.

Methods: Medical records of the consecutive patients who underwent LS or open surgery (OS) for PPU at five hospitals between January 2009 and December 2019 were retrospectively reviewed.

Comparative study of nitrogen doped multi walled carbon nanotubes grafted with carboxy methyl cellulose hybrid composite by inverse gas chromatography and its UV photo detectors application.

In this present work, the synthesis of nitrogen doped multi walled carbon nanotubes (N-MWCNTs) grafted Sodium-carboxy methyl cellulose (Na-CMC) hybrid composite was carried out via thermal reduction process. The hybrid composites were thermodynamically characterized by inverse gas chromatography (IGC) and compared to Na-CMC particles. The results were obtained by using 14 different IGC methods and models.

Effect of chemotherapy and radiotherapy on cognitive impairment in colorectal cancer: evidence from Korean National Health Insurance Database Cohort.

Objectives: We investigated the risk of chemotherapy-related and radiotherapy-related cognitive impairment in colorectal cancer patients.

Methods: Medical use data of colorectal cancer patients were obtained from the Korean National Health Insurance Database from 2004 to 2018. We randomly selected 40% of all colorectal cancer patients (n=148,848).

Impact of COVID-19 on the care of acute appendicitis: a single-center experience in Korea.

Purpose: Coronavirus disease 2019 (COVID-19) affects healthcare systems worldwide; however, few studies have assessed the impact of COVID-19 on emergent surgical diseases. This study aimed to investigate the impact of COVID-19 on the care given to patients with acute appendicitis in Korea.

Methods: Between November 2019 and November 2020, 495 patients underwent laparoscopic surgery for acute appendicitis.