Publications by authors named "Chang-Shun He"
Article Synopsis
- The study examines how hypertension influences aortic remodeling in two mouse strains, revealing that while one strain exhibits adaptive changes, the other shows maladaptive responses.
- Histological analysis shows that the hypertensive 129S6/SvEvTac aortas adapt well, while C57BL/6 J aortas suffer from excessive inflammation and structural alterations.
- Computational models suggest that effective vasoconstriction and appropriate wall stress restoration in 129S6/SvEvTac aortas lead to proper remodeling, contrasting with the inflammation-driven issues in C57BL/6 J aortas due to inadequate vasoconstriction.
Human cortical organoids (hCOs), derived from human embryonic stem cells (hESCs), provide a platform to study human brain development and diseases in complex three-dimensional tissue. However, current hCOs lack microvasculature, resulting in limited oxygen and nutrient delivery to the inner-most parts of hCOs. We engineered hESCs to ectopically express human ETS variant 2 (ETV2).
View Article and Find Full Text PDF[Endovascular repair of an iliac artery aneurysm after endovascular aneurysm repair with handmade iliac branch device: a case report].
Beijing Da Xue Xue Bao Yi Xue Ban
October 2015
An involved internal iliac artery is usually embolized when performing endovascular aneurysm repair for aortoiliac or isolated iliac artery aneurysm.This can lead to complications such as buttock claudication,colon ischaemia and erectile dysfunction.Iliac branch device (IBD) is an endograft designed specifically for iliac bifurcation to preserve internal iliac flow.
View Article and Find Full Text PDF[Endovascular treatment of a rare type of aortic arch aneurysm derived from the fourth aortic arch].
Beijing Da Xue Xue Bao Yi Xue Ban
June 2015
Objective: To report a rare type of aortic arch aneurysm.
Methods: Three cases of aortic arch aneurysm derived from the fourth aortic arch were retrospectively analyzed. The pathogenesis and treatment of this type of aortic arch aneurysm were investigated.
[Diagnosis and surgical treatment results of angio-Behçet syndrome: an analysis of 26 patients].
Zhonghua Wai Ke Za Zhi
March 2012
Objective: To analyze the diagnosis and surgical treatment results of angio-Behçet syndrome.
Methods: The clinical data of pre-operation diagnosis, surgical treatment methods and prospective efficacy of 26 patients who were diagnosed as Behçet syndrome between January 2003 and April 2011 was analyzed retrospectively. There were 23 male and 3 female patients, aging from 20 to 76 years with a mean of (37 ± 6) years.