Aim: To construct an immune-related prognostic signature (IPS) that can distinguish and predict prognosis in uveal melanoma (UM).
Methods: The transcriptomic data and clinicopathological information of 80 UM patients were extracted from the TCGA database. These patients were randomly assigned to a training and a testing set.
Aim: To identify the mutations in RS1 gene associated with typical phenotype of X-linked juvenile retinoschisis (XLRS) and a rare condition of concomitant glaucoma.
Methods: Complete ophthalmic examinations were performed in the proband. The coding regions of the RS1 gene that encode retinoschisin were amplified by polymerase chain reaction and directly sequenced.
Zhonghua Yi Xue Za Zhi
August 2012
Objective: To discuss an innovative model of blindness prevention targeting the elimination of cataract blindness.
Methods: The patients aged 50 or above underwent one mature procedure of small incision cataract surgery. It was performed at our class 3A hospital with advanced medical skills, superior medical services and management system.