Publications by authors named "Chang-Qing Yan"
[Resveratrol attenuates cardiac function impairment in plateau hypobaric hypoxia rats].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
November 2022
Article Synopsis
The present study explored the effect of long non-coding RNA-human ovarian cancer-specific transcript 2 (LncRNA-HOST2) on cell proliferation, migration, invasion and apoptosis of human hepatocellular carcinoma (HCC) cell line SMMC-7721. HCC tissues and adjacent normal tissues from 162 HCC patients were collected. The HCC cell lines were assigned into the control group (regular culture), negative control (NC) group (transfected with siRNA) and experimental group (transfected with Lnc-HOST2 siRNA).
View Article and Find Full Text PDF[The significance of VEGF siRNA and bFGF siRNA in invasion and proliferation of pancreatic carcinoma cell].
Zhonghua Wai Ke Za Zhi
April 2010
Objective: To investigate the relationship between expression of angiogenic factors and invasion and proliferation of pancreatic cancer cell.
Methods: The three pancreatic cancer cell lines of SW1990, Panc-1 and PCT-3 were divided into four groups respectively: control group, VEGF siRNA group, bFGF siRNA group and VEGF siRNA + bFGF siRNA group. The expression and the secretion of VEGF and bFGF in the three cell lines were inhabited by VEGF siRNA and bFGF siRNA.
[Expression of angiogenic factors in pancreatic carcinoma cell and their significance].
Zhonghua Wai Ke Za Zhi
May 2009
Article Synopsis
- The study aimed to explore how angiogenic factors influence the invasion and growth of pancreatic cancer cells.
- Various pancreatic carcinoma cell lines were examined for the expression and secretion levels of these factors using techniques like RT-PCR and ELISA.
- Results indicated that different cell lines exhibited varying levels of invasion and proliferation, with Panc-1 showing the highest expression of key angiogenic factors, suggesting a link between these factors and cancer aggressiveness.
Objective: To investigate the relationship between TSP-1, Angiostatin and Endostatin serum concentrations and progression of pancreatic adenocarcinoma.
Methods: Fifty-six patients with suspected pancreatic cancer were enrolled in the study and divided into resectable group (n = 32) and unresectable group (n = 24) according to evaluation and staging with dual phase helical CT. Histopathologic examinations included postoperative final pathology and preoperative fine needle biopsies.
Diagnosis and management of isolated pancreatic tuberculosis: experience of 13 cases.
Chin Med Sci J
September 2007
Objective: To analyze the diagnosis and treatment of pancreatic tuberculosis.
Methods: Retrospectively reviewed and summarized 13 pancreatic tuberculosis patients' clinical information, presentation, diagnostic methods, therapeutic approaches, and prognosis from 1958 to 2004 at Peking Union Medical College Hospital.
Results: All cases presented a wide series of symptoms, including fever in 6 cases, upper abdominal tenderness in 13, epigastric mass in 4, obstructive jaundice in 3, night sweat in 4, weight loss in 7, hypersplenotrophy and hypersplenism in 1, and being complicated with tuberculosis of other organs in 3.
Objective: To investigate the relationship between VEGF, bFGF and IGF-1 serum concentration and progression of pancreatic carcinoma.
Methods: Fifty-six patients with pancreatic carcinoma were divided into resectable group (n = 32) and unresectable group (n = 24). Another group was normal group (n = 20).