Publications by authors named "Chang-Qing Shen"

Article Synopsis
  • - The article discusses heat stress (HS) in mammals, which disrupts their thermal balance and negatively impacts the development of oocytes and embryos, resulting in economic losses in the livestock industry.
  • - It outlines the mechanisms by which HS affects embryonic development, including the generation of reactive oxygen species, endocrine disruption, and molecular changes.
  • - The article also explores strategies to mitigate HS effects, such as using antioxidants, enhancing mitochondrial function, gene editing, and improving the animals' rearing environment.
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Objective: Macrophage migration inhibitory factor (MIF) has been suggested as a pivotal regulator of innate immunity and inflammatory. The aim of this study was to measure serum circulating levels of MIF in relation to the degree of the severity of autism spectrum disorders (ASD).

Methods: One hundred and two Chinese children with ASD and same their age-sex matched typical development children were included.

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Terpinen-4-ol, the major constituent of tea tree oil, has been reported to have anti-inflammatory effect. However, whether terpinen-4-ol could attenuate LPS-induced inflammation in lung tissues remains unclear. In the present study, we aimed to investigate the protective effects of terpinen-4-ol on LPS-induced acute lung injury (ALI) in mice.

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Transforming growth factor beta receptor 2 (TGFBR2) plays a central role in normal heart development, and we investigated whether TGFBR2 polymorphism confers the risk of congenital ventricular septal defect (CVSD). The case-control study included 115 CVSD children and 188 healthy children in a Chinese population. TGFBR2 rs6785358 polymorphism was genotyped with polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).

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