Publications by authors named "Chang Xing Chen"
Article Synopsis
- The study aimed to determine if bone marrow mesenchymal stem cells (BMMSCs) can help repair periodontal bone through a specific signaling pathway (PHD2/HIF-1) when faced with inflammation.
- Researchers tested BMMSCs modified to silence the PHD2 gene in a lab environment simulating inflammation caused by bacteria, observing improved cell differentiation and bone health.
- Results showed that silencing PHD2 boosted BMMSC function and increased vascular growth factors, suggesting that this genetic modification could be a promising method for treating bone loss due to inflammation.
[Studies on the chemical constituents from the fruit of Aristolochia debilis].
Zhong Yao Cai
August 2010
Objective: To study the chemical constituents of the fruit of Aristolochia debilis.
Methods: The compounds were isolated by chromatographic techniqcue and crystal methods, the structures were elucidated by spectrum analysis.
Results: 8 compounds were isolated from the dry fruit of Aristolochia debilis which were aristolochic acid I (1), aristolochic acid II (2), aristolochic acid III (3), aristolochic acid III a(4), aristolochic acid VII a (5), aristolactam I (6), aristolactam II (7) and aristolactam III a (8).