Influence of parasympathetic modulation in doppler mitral inflow velocity in individuals without heart disease.

Background: The relation between left ventricular filing velocities determined by Doppler echocardiography and autonomic nervous system function assessed by heart rate variability (HRV) is unclear. The aim of this study was to evaluate the influence of the autonomic nervous system assessed by the time and frequency domain indices of HRV in the Doppler indices of left ventricular diastolic filling velocities in patients without heart disease.

Methods: We studied 451 healthy individuals (255 female [56.