Publications by authors named "Chang Hoon Song"

Article Synopsis
  • Recent advances in treating resectable non-small cell lung cancer (NSCLC), particularly the ADAURA trial, highlight the effectiveness of osimertinib for patients at high risk of relapse, necessitating further studies to identify these specific subgroups.
  • A study analyzing data from 3,176 NSCLC patients concluded that 14.0% experienced late recurrence, with the EGFR-mutant subgroup being particularly studied for relapse factors.
  • Key factors influencing postoperative relapse in patients with EGFR mutations include age, pathologic N and TNM stages, pleural invasion status, and type of surgery, indicating that those with advanced conditions or specific surgical histories are at greater risk.
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Colorectal cancer is the third most common cancer in Korea and the third leading cause of death from cancer. Treatment outcomes for colon cancer are steadily improving due to national health screening programs with advances in diagnostic methods, surgical techniques, and therapeutic agents..

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The adoption of LiCuO has drawn interest as a Li-excess cathode additive for compensating irreversible Li loss in anodes during cycling, which would move forward high-energy-density lithium-ion batteries (LIBs). LiCuO provides a high irreversible capacity (>200 mAh g) in the first cycle and an operating voltage comparable with commercial cathode materials, but its practical use is still restricted by the structural instability and spontaneous oxygen (O) evolution, resulting in poor overall cycling performance. It is thus crucial to reinforce the structure of LiCuO to make it more reliable as a cathode additive for charge compensation.

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In this study, cobalt films were deposited by plasma enhanced atomic layer deposition (PEALD) with cobaltocene (Co(Cp)₂) using two different very high frequency (VHF) NH₃ plasmas (60 MHz, 100 MHz), and the effect of different frequencies of VHF on the characteristics of NH₃ plasmas and the properties of cobalt films were investigated. It is found that the higher frequency showed the higher plasma density at the same input power and, the NH radicals, which are required to remove the ligands of the cobalt precursor during the plasma exposure step in the ALD cycle, were higher at 100 MHz than those at 60 MHz. The RMS surface roughness and carbon impurity percentage of the deposited cobalt films were lower at the higher frequency possibly indicating denser films due to more active surface reactions at the higher frequency.

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Aim: To analyze the treatment outcomes, patterns of failures and prognostic factors for patients with anal cancer treated with radiotherapy (RT).

Materials And Methods: Between January 2000 and December 2015, 83 patients with anal squamous cell carcinoma were treated with definitive RT. The median RT dose applied to the primary carcinoma site was 55 (range=45-64) Gy.

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Background: Adolescent obesity and hypertension are global public health issues. The burden of adolescent obesity and hypertension in Peru is unclear. The aim of this study was to determine the prevalence of obesity and hypertension and their relationship among school-attending adolescents and to assess the need for health-promoting school programs in the study area.

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Article Synopsis
  • The study investigates the role of specific signaling proteins in the MAPK and PI3K pathways to find potential markers for predicting early relapse in invasive breast cancer patients.
  • Immunohistochemical analyses were conducted on tumor samples from 212 patients, focusing on protein expressions like HSP90 and PI3K-p110alpha, and their correlation with relapse-free survival.
  • Results indicate that coexpression of HSP90 with PI3K-p110alpha or loss of PTEN correlates with poorer prognosis, particularly in HER2-positive breast cancer cases.
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Purpose: To assess clinical outcomes and complications in patients with non-small-cell lung cancer (NSCLC) treated with helical tomotherapy (HT) with or without chemotherapy.

Methods And Materials: Data from 37 NSCLC patients treated between January 2007 and August 2008 were analyzed retrospectively. Twenty-eight patients had Stage III disease.

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Objectives: To analyze the impact of neoadjuvant chemotherapy (CT) on the treatment of early-stage nasopharyngeal carcinoma (NPC) as compared with radiotherapy (RT) alone.

Methods: We analyzed retrospectively the outcome of 60 previously untreated and histologically confirmed early-stage NPC patients treated with either RT alone or with neoadjuvant CT followed by RT (CT/RT) at the Seoul National University Hospital between 1986 and 2004. Neoadjuvant CT consisted of three cycles with 5-fluourouracil and cisplatin.

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Aim: The objective of this study was to assess whether Nd:YAG laser myringotomy has a negative effect on the cochlea.

Materials And Methods: Ten adult guinea pigs with a normal Preyer's reflex were treated by myringotomy with an Nd:YAG laser (power output 8-10W) under surgical microscopic guidance. Preoperative and immediately postoperative hearing tests were performed using auditory brainstem response.

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Purpose: An impairment of anastomotic blood flow (ABF) and the resulting hypoxia readily lead to the complications such as leakage and stricture. We performed an animal study to evaluate the effect of anchoring suture for minimizing the impairment of ABF caused by tensile loading.

Materials And Methods: An end-to-side jejunojejunostomy was done in 20 rats, and this followed the modeling of a human end-to-side esophagojejunostomy.

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