A recoverable hydrophilic deep eutectic solvent for efficient extraction of polyphenolic compounds from raspberry root.

Green deep eutectic solvents (DESs) are widely used to extract bioactive components from plant biomass; however, hydrophilic DES and bioactive component isolation methods have not been developed. In this study, we synthesized hydrophilic DES (CL-CA-DES) using citric acid and choline chloride. We combined this with environmentally friendly anion- and cation-exchange resin column chromatographic isolation methods.

Seven new species and four new records of Psychomyiidae (Insecta, Trichoptera) from China.

Seven new species of the family Psychomyiidae Walker, 1852 are described and illustrated from China; they are , , , , , , and The genus is reported for the first time from mainland China. In addition, four psychomyiids are found to be new to the Chinese caddis fauna: Malicky & Chantaramongkol, 1993; Malicky, 1979; Malicky & Chantaramongkol, 1993; and Johanson & Oláh, 2008. Moreover, Li, Qiu & Morse, 2021 is reviewed and synonymized with Malicky, 2020.

Description of adult female, larva, and pupa of Glossosoma (Lipoglossa) kamael Malicky 2012 (Trichoptera: Glossosomatidae) associated by COI sequences from China.

The adult female, larva, and pupa of Glossosoma (Lipoglossa) kamael Malicky 2012 from Qinghai Province, China, are described and illustrated. Molecular associations are based on COI sequences. The immature stages of the subgenus Lipoglossa are described for the first time.

Five new species of Tinodes (Trichoptera: Psychomyiidae) from China.

Five new species of genus Tinodes Curtis 1834 from China are described, illustrated, and diagnosed based on distinctive characters of male genitalia, including Tinodes falcata n. sp., T.

New species of the genus Curtis, 1834 (Trichoptera, Molannidae) in China inferred from morphology and DNA barcodes.

The male adult of Ge, Peng & Sun is described and illustrated based on material collected in Si-chuan, China. It could be diagnosed by the subtriangular superior appendages when viewed dorsally, and by the mesal appendages each having a slender thorn and inferior appendages with a tiny inner process. Based on morphology of genitalia, we provide a dichotomous key to adult males of from the Oriental region.

The First Report of the Genera and (Trichoptera: Xiphocentronidae) from China, with Descriptions of Two New Species.

The genera Mosely 1948 and Schmid 1982 are recorded in China for the first time. In this study, two new species, sp. nov.

Four new species of Psychomyia (Trichoptera: Psychomyiidae) from China, with re-descriptions of two species.

Four new species of the genus Psychomyia from China are described, illustrated and diagnosed: P. complexa n. sp.

A new species of Micardia Butler, 1878 (Lepidoptera, Noctuidae, Eustrotiinae) from China.

The genus Micardia Butler, 1878 was described based on M. argentata (the type species; Fig. 1) and M.

Descriptions of larvae of three species of Hydropsyche (Trichoptera, Hydropsychidae) from China.

Twenty-one individuals of Hydropsyche from An-hui and Zhe-jiang Provinces, China, were examined and their DNA barcode sequences were generated and analyzed. The larvae and males of H. arion, H.

Descriptions of pupae of two species from China (Insecta, Trichoptera, Hydropsychidae).

Pupae of two Hydropsyche species collected from Zhe-jiang Province, China, were examined and their barcode sequences were generated and analyzed. The pupae of H. simulata and H.

Fragmentation characteristics of hydroxycinnamic acids in ESI-MS by density functional theory.

This work aims to analyze the electrospray ionization multistage mass spectrometry (ESI-MS ) fragmentation characteristics of hydroxycinnamic acids (HCAs) in negative ion mode. The geometric parameters, energies, natural bond orbitals and frontier orbitals of fragments were calculated by density functional theory (DFT) to investigate mass spectral fragmentation mechanisms. The results showed that proton transfer always occurred during fragmentation of HCAs; their quasi-molecular ions ([M - H] ) existed in more than one form and were mainly with the lowest energy.

New species, new records, and new collection data of from China (Trichoptera: Rhyacophilidae).

Four new species of Rhyacophila, R. acanthoida n. sp.

Notes on the Rhyacophila scissa species group with description of two new taxa from China (Trichoptera, Rhyacophilidae).

One new species, R. meniscoides n. sp.

Pharmacokinetics and disposition of monoterpene glycosides derived from Paeonia lactiflora roots (Chishao) after intravenous dosing of antiseptic XueBiJing injection in human subjects and rats.

Aim: Monoterpene glycosides derived from Paeonia lactiflora roots (Chishao) are believed to be pharmacologically important for the antiseptic herbal injection XueBiJing. This study was designed to characterize the pharmacokinetics and disposition of monoterpene glycosides.

Methods: Systemic exposure to Chishao monoterpene glycosides was assessed in human subjects receiving an intravenous infusion and multiple infusions of XueBiJing injection, followed by assessment of the pharmacokinetics of the major circulating compounds.

A new species of Stenopsyche, with descriptions of larvae and females of some species associated by gene sequences (Insecta: Trichoptera).

Twenty-seven individuals of Stenopsyche from An-hui, Shan-xi and Si-chuan provinces, China, were examined and their DNA (mtCOI) sequences were extracted and analyzed. The larva, male, and female of a new species, S. huangshanensis sp.

[Mechanism of biological actions of quercetin based on biomolecular network].

The mechanism of biological actions of quercetin was studied by using metabolomic method and biomolecular network. HPLC-MS was used to analyze the serum metabolome in rats of blank group and quercetin administration group rats, and MS data were processed by MATLAB software. With multivariate statistical analysis of serum metabolite profiles, a clear separation among blank group and quercetin administration group was achieved, potential biomarkers were selected according to the parameters of variable importance in the projection (VIP) and identified according to MS information and database retrieval.

The Stenopsyche simplex Species Group from China with descriptions of three new species (Trichoptera: Stenopsychidae).

The Chinese Stenopsyche simplex Group is revised for the first time since Weaver's (1987) revision. The group includes 14 described species and 3 new species. Two diagnostic subgroups were recognized by Schmid (1959).

Fasudil protects hippocampal neurons against hypoxia-reoxygenation injury by suppressing microglial inflammatory responses in mice.

Rho kinase (ROCK) may play an important role in regulating biological events of cells, including proliferation, differentiation and survival/death. Blockade of ROCK promotes axonal regeneration and neuron survival in vivo and in vitro, thereby exhibiting potential clinical applications in spinal cord damage and stroke. Our previous studies have demonstrated that Fasudil, a selective ROCK inhibitor, induced neuroprotection in vitro.

Protective effects of Flos lonicera extract on acute liver injury by dimethylnitrosamine-induced in rats.

The aim of this study is to investigate effects of Flos lonicera extract (FLE) on acute liver injury model rats which induced by 35 mg/kg dimethylnitrosamine (DMN). Model rats were divided into hepatic injury control group (administrated with water), FLE group (administrated with FLE) and silymarin group (administrated with silymarin which is hepatotherapeutic drug) as positive control. They were examined including ALT, AST, ALP, gamma-GT, ALB and TP levels in serum, and MDA, GPx levels in liver tissue.

Therapeutic potential of experimental autoimmune encephalomyelitis by Fasudil, a Rho kinase inhibitor.

The migration of aberrant inflammatory cells into the central nervous system plays an important role in the pathogenesis of demyelinating diseases potentially through the Rho/Rho-kinase (Rock) pathway, but direct evidence from human and animal models remains inadequate. Here we further confirm that Fasudil, a selective Rock inhibitor, has therapeutic potential in a mouse model of myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE). The results show that Fasudil decreased the development of EAE in C57BL/6 mice.

Fasudil, a Rho kinase inhibitor, drives mobilization of adult neural stem cells after hypoxia/reoxygenation injury in mice.

Rho kinase (ROCK) is important in fundamental processes of cell proliferation and survival. Blockade of ROCK promotes stem cell survival in vitro and axonal regeneration in vivo, exhibiting therapeutic potential such as spinal cord injuries and stroke. Here, we used the model of hypoxia/reoxygenation (H/R) injury to explore the possibility whether Fasudil, a ROCK inhibitor in clinical application for subarachnoid hemorrhage and stroke, mobilizes adult neural stem cells in vivo.