Exploring the Benefits of Herbal Medicine Composite 5 (HRMC5) for Skin Health Enhancement.

The skin, as the body's largest organ, is vital for protecting against environmental stressors, regulating temperature, and preventing water loss. Here, we examined the potential of a mixture of five traditional Korean herbal extracts-, , , , and -referred to as herbal medicine composite 5 (HRMC5) for enhancing skin health and managing menopausal symptoms. High-performance liquid chromatography identified 14 bioactive compounds, including flavonoids, phenolic acids, anthraquinones, and alkaloids.

Toxicity of Lavandula angustifolia oil constituents and spray formulations to insecticide-susceptible and pyrethroid-resistant Plutella xylostella and its endoparasitoid Cotesia glomerata.

Background: Plutella xylostella is one of the most serious insect pests of cruciferous crops. This study was conducted to determine the toxicity of 21 constituents from Lavandula angustifolia essential oil (LA-EO) and another 16 previously known LA-EO constituents and the toxicity of six experimental spray formulations containing the oil (1-6 g L(-1) sprays) to susceptible KS-PX and pyrethroid-resistant JJ-PX P. xylostella larvae, as well as to its endoparasitoid Cotesia glomerata adults.

Fumigant toxicity of basil oil compounds and related compounds to Thrips palmi and Orius strigicollis.

Background: This study was aimed at assessing the fumigant toxicity to adult Thrips palmi (a serious insect pest) and Orius strigicollis (a beneficial predator insect) of basil (Ocimum basilicum) essential oil compounds and structurally related compounds using vapour-phase toxicity bioassays.

Results: Against adult T. palmi, linalool (LD50 0.

A rapid and highly sensitive UPLC-MS/MS method using pre-column derivatization with 2-picolylamine for intravenous and percutaneous pharmacokinetics of valproic acid in rats.

A rapid, highly sensitive and specific ultra-performance liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS) for the detection of valproic acid (VPA) in rat plasma following the topical application was developed and validated. This method was carried out with pre-column derivatization using 2-picolylamine (PA) which reacts with the carboxylic acid group of VPA. The derivatization was completed in 10min and the resulting PA-VPA derivative enabled the sensitive detection of VPA in selected reaction monitoring (SRM) mode.

Fumigant toxicity of plant essential oils to Thrips palmi (Thysanoptera: Thripidae) and Orius strigicollis (Heteroptera: Anthocoridae).

The fumigant toxicity of 92 plant essential oils to adult Thrips palmi Karny (Thysanoptera: Thripidae) and Orius strigicollis Poppius (Heteroptera: Anthocoridae) was examined by using a vapor phase toxicity bioassay and compared with those of dichlorvos, emamectin benzoate, spinosad, and thiamethoxam, four commonly used insecticides. Responses varied according to oil type and insect species. As judged by 24-h LC50 values, pennyroyal oil (2.