Publications by authors named "Chandu Siripuram"

Background: Diabetes mellitus (DM) increases the risk of left ventricular dysfunction (LVD), which can progress to heart failure if undetected. Echocardiography, a non-invasive and cost-effective imaging tool, provides real-time assessment of left ventricular (LV) function and enables early detection of myocardial dysfunction using advanced techniques such as tissue Doppler imaging and strain analysis. Diabetic patients are particularly prone to LVD due to chronic hyperglycemia, insulin resistance, and systemic inflammation, leading to myocardial fibrosis, microvascular dysfunction, and oxidative stress.

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Coffee has long been popular worldwide. The rise in lifestyle-related diseases such as cardiovascular disease, diabetes, stroke, dementia, and others has motivated coffee usage and illness prevalence studies. Some studies show coffee consumers are at risk for such diseases, whereas others show its active components protect them.

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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an uncommon genetic disorder that affects small blood vessels in the brain. It leads to neurological symptoms, disability-adjusted life years, and difficult emotional and physical situations for patients and their families. As unusual brain symptoms appear, it becomes important to understand the different clinical manifestations of CADASIL.

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Article Synopsis
  • Thyroid hormones significantly influence metabolic processes in the liver, and dysfunction in thyroid levels can affect liver function, particularly in the North Karnataka region, where dietary and environmental factors play a role in thyroid disorders.
  • The study aims to investigate the link between thyroid-stimulating hormone (TSH) levels and liver function, as well as assess the impact of TSH on blood pressure and the occurrence of related health issues in the local population.
  • A retrospective review of 75 patients revealed that 21.4% had thyroid irregularities, primarily hypothyroidism, and various comorbidities such as diabetes, anemia, and hypertension were documented among the participants, highlighting the interconnectedness of thyroid health and other metabolic conditions.
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In older adults, diagnosing, treating, and preventing urinary tract infections (UTIs) can be challenging. This case is of an 82-year-old female of white descent, who was admitted to a post-acute care facility following hospitalization for delirium and a UTI. Hypoactive delirium may be the only clinical manifestation of recurrent UTI.

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