CoTCoNet: An optimized coupled transformer-convolutional network with an adaptive graph reconstruction for leukemia detection.

Background: Swift and accurate blood smear analyses are crucial for diagnosing leukemia and other hematological malignancies. However, manual leukocyte count and morphological evaluation remain time-consuming and prone to errors. Additionally, conventional image processing methods struggle to differentiate cells due to visual similarities between malignant and benign cell morphology.