Plasma-based fast-gelling biohybrid gels for biomedical applications.

Blood based biomaterials are widely researched and used in different biomedical applications including cell therapy, drug delivery, sealants etc. due to their biocompatibility and biodegradability. Blood derived gels are successfully used in clinical studies due to the presence of fibrinogen and several platelet growth factors.

Synthesis, characterization and application of biodegradable polymer grafted novel bioprosthetic tissue.

Animal tissue has an extended history of clinical use in applications like heart valve bioprosthesis devices, cardiovascular surgical applications etc. but often does not last long after implantation in the body due to rapid unwanted degradation. The goal of this work is to develop novel composite biomaterials by grafting biological tissue with synthetic, biodegradable polymers.

A 5-year hospital prevalence of child and adolescent psychiatric disorders from central India.

Objective: To examine the 5-year hospital prevalence of child and adolescent mental disorders from Central India.

Methods: Using systemic random sampling method, of the 4410 families screened, 4278 children (607 aged 0 to 3 y and 3671 between 4 to 16 y) attending outpatient services of department of pediatrics at the tertiary rural hospital from June 2006 through December 2010 were evaluated. Standardized appropriate psychometric tools were used for both groups.

Formulation and characterization of radio-opaque conjugated in situ gelling materials.

X-ray visibility is an integral design component of in situ gelling embolization systems for neurovascular treatment. The goals of this project included the synthesis and characterization of a unique intrinsically radio-opaque in situ gelling material for neurovascular embolization. The gels formed using Michael-Type Addition between pentaerythritol tetrakis 3-mercaptopropionate (QT) thiols and poly(propylene glycol) diacrylate (PPODA) with the addition of the new material Iodobenzoyl poly(ethylene glycol) acrylate (IPEGA), a radio-opaque agent, synthesized successfully as confirmed with (1)H NMR.