Assessment of vitamin D levels in patients with oral potentially malignant disorders and oral squamous cell carcinoma-A cross-sectional study.

Objectives: The aim of this study was to assess and compare the serum and salivary levels of Vitamin D in patients with oral potentially malignant disorders (OPMD) and Oral squamous cell carcinoma (OSCC) with healthy controls.

Method: This cross-sectional study was carried out among 60 patients reporting to the department of Oral Medicine and Radiology, and included patients with OPMDs, OSCC and healthy controls. The Vitamin D levels were estimated using the chemiluminescence immunoassay.

Insight in to the Awareness of CBCT as an Imaging Modality in the Diagnosis and Management of ENT Disorders: A Cross Sectional Study.

The advent of Cone-beam computed tomography (CBCT), has revolutionized 3D imaging in dentistry. CBCT has enormous potential to be used as an alternative imaging modality by Otolaryngologists. But their knowledge regarding CBCT is limited.

Bioinformatics analysis of miRNA and its associated genes to identify potential biomarkers of oral submucous fibrosis and oral malignancy.

Background: MicroRNAs are a group of non-coding RNA that controls the gene expression. The interaction between miRNA and mRNA is thought to be dynamic. Oral cancer "The cancer of mouth" is quite prevailing in developing countries.

Age estimation in Western Indian population by Cameriere's and Drusini's methods.

Objectives: The aim of the present study is to determine applicability of Cameriere's and Drusini's methods in Western Indian population.

Methodology: Panoramic radiographs of total 300 Gujarati individuals, equally divided into four study groups were studied by two investigators. The pulp/tooth area ratio (AR) were calculated for maxillary and mandibular canines and tooth coronal indexes (TCI) i.

Comparative evaluation of effectiveness of autologous platelet rich plasma and intralesional corticosteroids in the management of erosive oral Lichen planus- a clinical study.

Purpose: Oral Lichen planus is a potentially malignant autoimmune disorder, characterized by burning and pain in the affected mucosa which reduces the quality and comfort of patient's life. Various treatment modalities have been documented for OLP but due its malignant potential the alternative therapeutic approaches with least or no side effects are being in demand. One of such, yet unexplored treatment is Platelet rich plasma (PRP).

Medicinal management of oral submucous fibrosis in the past decade- A systematic review.

Introduction: Oral submucous fibrosis (OSMF) is a potentially malignant disorder with a high rate of malignant transformation. It is associated with chewing of areca nut and tobacco products with a high global prevalence, particularly in the southeast Asian countries. A wide range of treatment modalities are available, ranging from corticosteroids, antioxidants, nutritional supplements to herbal medicines but lacks a reliable treatment regimen.

Causal inference and directed acyclic graph: An epidemiological concept much needed for oral submucous fibrosis.

Oral submucous fibrosis (OSMF), although already established as an oral potentially malignant disorder (OPMD), still stands over a weak bridge because of its controversial pathogenesis. There has been tremendous work on this disease since 1962, surprisingly, we are unsuccessful in finding the exact causation of OSMF. The potential cause for this is either a lack of systematically performed clinical observational studies or over-interpreted inferences of the presented results.

Oral submucous fibrosis in children and adolescents: Analysis of 36 cases.

Oral submucous fibrosis (OSMF) is a chronic debilitating irreversible oral potentially malignant disorder affecting any part of the oral cavity. It is usually seen in adults but rarely noticed in children and adolescents. Since the paucity of the cases, there exists a gap of knowledge in the causative habits, root reasons of habit initiation, age of habit initiation, and the common clinical representation of this disorder.

Reasons for Initiation of Areca Nut and Related Products in Patients with Oral Submucous Fibrosis within an Endemic Area in Gujarat, India.

: While the patterns of consumption of areca nut and its by-products (ANBP) vary across South Asia and the rest of the world, all users share the probable severe outcome of oral submucous fibrosis (OSMF), and this is well reported. The role of psychosocial drivers of habit initiation and addiction is reported less. : To reveal the burden of ANBP abuse, exploring the psychosocial relationship between sex, age at first exposure (AFE), the reason for initiation (RFI) with the type of habit (TOH).

Age- and sex-related mandibular dimensional changes: A radiomorphometric analysis on panoramic radiographs.

Introduction: Mandible undergoes age- and sex-related structural changes similar to other bones of the body. Thus, morphometric analysis of the mandible helps in age and sex determination.

Aim: To investigate the influence of age and sex on the mandible by measuring three parameters, i.

Oral submucous fibrosis: a contemporary narrative review with a proposed inter-professional approach for an early diagnosis and clinical management.

Oral Submucous fibrosis (OSMF) has traditionally been described as "a chronic, insidious, scarring disease of the oral cavity, often with involvement of the pharynx and the upper esophagus". Millions of individuals are affected, especially in South and South East Asian countries. The main risk factor is areca nut chewing.

Proposed clinical definition for oral submucous fibrosis.

Oral Submucous Fibrosis (OSMF) is an insidious, chronic, complex, crippling, debilitating, irreversible, progressive, scarring, potentially malignant and collagen metabolic disorder, induced by a known carcinogen areca nut; wherein the oral mucosa, and occasionally the pharynx and esophagus is subjected to various pathological changes with significant clinical manifestations at different stages of progression, leading to functional morbidity; and with a risk of malignant transformation in the overlying epithelium. Although the condition is mainly diagnosed based on classic clinical manifestations, the commonly used existing definition for oral submucous fibrosis is primarily based on histological features. The authors have conducted extensive clinical research studies on OSMF and intends to propose a new clinical definition as 'a debilitating, progressive, irreversible collagen metabolic disorder induced by chronic chewing of areca nut and its commercial preparations; affecting the oral mucosa and occasionally the pharynx and esophagus; leading to mucosal stiffness and functional morbidity; and has a potential risk of malignant transformation.

Sex determination from tooth pulp deoxyribonucleic acid using polymerase chain reaction.

Introduction: In this fast era of numerous unwanted disasters and because of the severely devastated and degenerated body remains, personal identification of unknown remains has become the most difficult and challenging task. In such instances, dental pulp plays a vital role in identification through deoxyribonucleic acid (DNA).

Aim: The aim of the study is to determine sex from tooth pulp tissues by DNA analysis using polymerase chain reaction amplification method under different environmental conditions.

A novel clinical protocol for therapeutic intervention in oral submucous fibrosis: An evidence based approach.

Oral submucous fibrosis (OSMF) is a chronic, progressive, debilitating, scarring and crippling disorder of the oral cavity. It is a potentially malignant oral disease which predominantly affects people of South and Southeast Asia, especially Indian subcontinent, where chewing of areca nut and its commercial preparation is rampant. However, due to increase in immigration of people from the Indian subcontinent, the health professionals in many developed countries do come across this disease very often.

Morphometric analysis of mandibular ramus for sex determination on digital orthopantomogram.

Background: Identification of sex from skeletal remains is an important tool in forensic science. Mandibular ramus can be used for sex determination either on dry mandible or through orthopantomogram (OPG).

Aim: To determine the sex from mandibular ramus using digital OPG.

Estimation of Serum Protein in Oral Potentially Malignant Disorders and Oral Malignancy - A Cross-Sectional Study.

Introduction: In carcinogenesis, increased oxidative stress and weakened antioxidant defense produces damage to the macromolecules like proteins. Thus, protein can act as potential biomarker in oral premalignant and malignant lesions.

Aim: To determine and compare the levels of serum proteins in Oral Submucuous Fibrosis (OSMF), Oral Leukoplakia (OL), Nicotina Stomatitis (NS), Oral Malignancy (OM) and Healthy Controls (HC).

Comparison of Therapeutic Efficacy of Placental Extract with Dexamethasone and Hyaluronic Acid with Dexamethasone for Oral Submucous Fibrosis - A Retrospective Analysis.

Introduction: Oral Submucous Fibrosis (OSMF) is a potentially malignant disease of the oral cavity associated with betel nut chewing. The management of OSMF has been a subject of controversy and no definitive and widely accepted treatment is currently available for this condition.

Aim: To retrospectively evaluate the therapeutic efficacy of two treatment regimens (placental extract with dexamethasone and hyaluronic acid with dexamethasone) for the treatment of OSMF.

Stafne's Bone Cavity: A Diagnostic Challenge.

Stafne's bone cavity is a rare, asymptomatic, unilateral oval shaped radiolucent defect in the posterior region of the mandible below the inferior alveolar canal. The prevalence ranges from 0.10% to 0.

Intraosseous calcifying epithelial odontogenic (Pindborg) tumor: A rare entity.

Calcifying epithelial odontogenic tumor (CEOT) is a locally aggressive, rare benign odontogenic neoplasm that accounts for <1% of all odontogenic tumors. It was first described by a Dutch pathologist Jens Jorgen Pindborg in 1955. It is most often located in the posterior mandible.

Morphological Study of Soft Palate by Using Computed Tomography-A Prospective Study.

Background: Soft palate is an important part of oro-naso-pharyngeal apparatus. The morphometric assessment of soft palate is well-performed on computed tomography (CT).

Aim: To evaluate the morphology of soft palate in healthy individuals by using Computed tomography.

Oral mucocele: A clinical and histopathological study.

Background: Oral mucocele is the most common benign minor (accessory) salivary gland lesion, caused due to mechanical trauma to the excretory duct of the gland. Clinically they are characterized by single or multiple, soft, fluctuant nodule, ranging from the normal color of the oral mucosa to deep blue. It affects at any age and is equally present in both sexes with highest incidence in second decade of life.

Osteochondroma of mandibular condyle: A clinic-radiographic correlation.

Osteochondroma (OC) of temporo mandibular joint is a rare, slow growing, benign tumor that causes a progressive enlargement of the condyle, usually resulting in facial asymmetry, temporo mandibular joint (TMJ) dysfunction, limited mouth opening and malocclusion. Pain is rarely associated with this tumor. OC is composed of cartilaginous and osseous tissues.

Mandibular adenomatoid odontogenic tumor: Radiographic and pathologic correlation.

Adenomatoid odontogenic tumor (AOT) is a rare tumor of epithelial origin comprising 3% of all the odontogenic tumors. It is a benign, painless, noninvasive, and slow-growing lesion, with a relative frequency of 2.2-13% and often misdiagnosed as an odontogenic cyst on clinical examination.

Hereditary ectodermal dysplasia: A retrospective study.

Background: Ectodermal dysplasia (ED) is a group of rare, inherited disorders characterized by sparse hair, missing teeth and inability to sweat.

Objective: To review and analyze cases of ED with an emphasis on clinical manifestations and parent's marriage history.

Methodology: The present retrospective study was conducted by assessing the clinical records of nineteen cases of ED, available in the archives of the department; for age, gender, family history of consanguineous marriage and clinical manifestations.

Van der Woude syndrome: report of two cases with supplementary findings.

Van der Woude syndrome (VWS) is a rare developmental disorder with an autosomal dominant inheritance and variable expressivity, occurring in about 1 of every 1,00,000-2,00,000 people. This syndrome is remarkably variable. It is characterized by orofacial manifestations like lower lip pits, cleft lip and/or cleft palate, hypodontia, cleft or bifid uvula, syngnathia, narrow high arched palate, ankyloglossia and hyper nasal voice.