Publications by authors named "Chandrajeet Dhara"
MicroRNA abundance as a particular biomarker for precisely identifying cancer metastases has emerged in recent years. The expression levels of miRNA are analyzed to get insights into cancer tissue detection and subtypes. Similar to other cancer types, the miRNA shows high levels of target mRNA dysregulation in association with non-small cell lung carcinoma (NSCLC).
View Article and Find Full Text PDFMicrobial virulence and biofilm formation stand as a big concern against the goal of achieving a green and sustainable future. Microbial pathogenesis is the process by which the microbes (bacterial, fungal, and viral) cause illness in their respective host organism. 'Nanotechnology' is a state-of-art discipline to address this problem.
View Article and Find Full Text PDFArticle Synopsis
- - Cancer is a leading global cause of death, with about 10 million fatalities yearly, prompting the need for effective treatments at cellular and genetic levels.
- - Immunotherapy, especially CAR T-cell therapy, shows promise in treating various cancers by using genetically modified T-lymphocytes to target and destroy tumors without needing a major histocompatibility complex.
- - Despite its potential, CAR T-cell therapy faces challenges like unique toxicities and complications in solid tumors; ongoing research aims to reduce these issues and enhance treatment effectiveness.