Publications by authors named "Chander R"

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  • * This case report highlights an elderly female patient with symptoms like vomiting and abdominal pain who was suspected to have cancer in her appendix. After surgery, she was diagnosed with MALT lymphoma affecting the appendix.
  • * Post-surgery, she experienced severe complications including blood clots leading to gangrene in her foot, resulting in both a thromboembolectomy and a below-knee amputation, illustrating the unusual association of lymphoma with blood clotting issues.
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  • The study investigated how individuals with mild cognitive impairment (MCI) and dementia perform on social cognition tests, comparing these results to those without cognitive impairment.
  • It involved a cross-sectional analysis of 321 older adults aged 80 and above, utilizing various social cognitive assessment tools and screening for levels of apathy and neurocognitive function.
  • Findings indicated that participants with dementia showed notably worse social cognitive abilities compared to those with MCI and no cognitive impairment, particularly in emotional recognition and perspective-taking tasks.
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The concurrent presentation of a low-grade appendiceal mucinous neoplasm (LAMN) and a borderline Brenner tumor (BT) of the ovary are exceedingly rare. Brenner tumors stand out as a particularly uncommon form, making up only around 5% of all benign epithelial tumors of the ovary. Among the ovarian Brenner, the borderline subtype is even rarer.

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Introduction: Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a rare genetic condition with a broad phenotypic presentation. This study aims to establish the first Australian cohort of individuals affected by CADASIL (AusCADASIL) and examine its clinical features and longitudinal course, and to investigate neuroimaging and blood biomarkers to assist in early diagnosis and identify disease progression.

Methods: Participants will be recruited from six study centres across Australia for an observational study of CADASIL.

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A sarcomatoid variant of urothelial carcinoma (SVUC) is an extremely rare variant, which accounts for only 0.1-0.3% of all urothelial carcinomas of the bladder.

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To determine the prevalence of anatomical variations of nasal cavity and paranasal sinuses of patients with chronic rhinosinusitis (CRS) on CT scan imaging. To correlate the Anatomical variations with the extent of CRS. 100 patients attending the ENT outpatient department with clinically diagnosed CRS were selected for study based on inclusion and exclusion criteria.

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  • This study compares three methods of assessing cognitive and affective empathy (behavioral, informant-report, and self-report) in a large adult sample (n=371) and finds that cognitive empathy measures show less agreement than affective ones.
  • While self-reports on affective empathy align with behavioral and informant-reports, cognitive empathy measures do not correlate with each other, highlighting issues with the validity of these assessments.
  • Informant-report measures are linked to better social functioning, and importantly, the effectiveness of these empathy assessments does not change with age, suggesting stable outcomes across different life stages.
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Objectives: Normal adult aging is associated with changes in social cognition. Although 4 social cognitive domains have been identified (social perception, theory of mind [ToM], affective empathy, and social behavior), no study has tested all 4 domains concurrently in a life-span sample, limiting understanding of the relative magnitude of age-related changes across domains. This study addresses this gap by providing the first assessment of all 4 social cognitive domains in an adult life-span sample.

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Abnormal vaginal discharge is common among the females of the reproductive age group. Vulvovaginitis caused by azole-resistant is rare. Recurrent vulvovaginal candidiasis (RVVC) causes significant patient distress and morbidity.

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Background: An elevated cardiovascular risk has been demonstrated in middle-aged individuals with onset of hair greying before the age of 30 years. Increased serum levels of pro-inflammatory cytokines, interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-α), indicate an ongoing state of chronic inflammation that is correlated with cardiovascular risk but have not been studied earlier in patients with early onset of hair greying.

Aim/objective: To study various cardiovascular risk markers including pro-inflammatory cytokines interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-α) in patients with premature canities.

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Benth (Lamiaceae) is a wild herb that possesses a number of biologically active phytomolecules. The aim of this study was to investigate comparative essential oils (EOs) composition and biological (antimicrobial and anti-diabetic) activities of from higher altitudes. Gas chromatography-mass spectrometry (GC/MS) and gas chromatography-flame ionisation detector (GC-FID) were carried out for the identification and quantification of EOs components.

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  • An 8-year-old girl presented with asymptomatic hyperpigmented plaques that developed in a linear pattern on her body, starting at age 1.
  • The condition began with an itching papule on her ankle which grew into larger plaques over a few months and eventually appeared on her hands and the left side of her body.
  • While most lesions increased in size, some partially resolved into hyperpigmentation, and there was no further progression noted in the last 6 months.
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Importance: Exact etiopathogenesis of chronic spontaneous urticaria (CSU) remains elusive. Infections, pseudoallergens, autoimmunity, and contact sensitization are various postulated factors. Few studies are available measuring cytokine levels in CSU.

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  • A 40-year-old male wrestler experienced asymptomatic hyperpigmentation on his arms for the past 10 years without any prior itching or irritation.
  • The dermatological examination indicated symmetrical brownish hyperpigmentation, and tests confirmed a diagnosis of macular amyloidosis (MA) through skin tissue analysis.
  • Treatment involved stopping the sand rubbing habit and applying tacrolimus ointment, leading to gradual improvement of the skin condition.
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Treatment gaps of 60-70%, reflecting, amongst many other factors, Human Resources shortfalls means that 150 million India never accessed mental healthcare. In Punjab, mental health training is required in primary health centers. A short-term synchronous training was conceptualized by the National Institute of Mental Health and Neurosciences.

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ST-elevation myocardial infarction (STEMI) is a cardiac emergency. However, multiple clinical disorders can cause ST-elevation ECG changes, one of which is pericarditis. Regional pericarditis is a less known clinical phenomenon that can mimic STEMI.

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Background: A burgeoning rise in the elderly subpopulation is being noted in India. This rise has already earned the designation as a shining nation by the United Nations/World Health Organization. This growth will take the elderly subpopulation to 324 million persons above 60 years by 2050.

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Introduction: Improving quality of care (QoC) for childbirth and sick newborns is critical for maternal and neonatal mortality reduction. Information on the process and impact of quality improvement at district and sub-district hospitals in India is limited. This implementation research was prioritized by the Haryana State (India) to improve the QoC for maternal and newborn care at the busy hospitals in districts.

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This study is an attempt to explain the nexus between health expenditures, GDP, human development index (HDI), CO emissions (COEM), renewable energy (RENE), financial development (FD) and electricity consumption (EC) using data from 2000Q to 2014Q for Brazil, India, China and South Africa. The study applies CIPS and CADF to determine the integration order. The tests confirmed the unique order of integration.

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