Publications by authors named "Chandanie Amila Wanigatunge"
Article Synopsis
- Carbapenem-resistant Enterobacteriaceae (CRE) are a significant health issue for cancer patients, with this study exploring their prevalence and the types of resistance genes present.
- Among 165 bacterial isolates from cancer patients, 57% were Enterobacteriaceae, and 46.8% of these were found to be carbapenem-resistant, with Klebsiella pneumoniae being the most common strain.
- The majority of the CRE strains produced carbapenemase, with the blaNDM gene being the most frequently detected, marking the first identification of blaVIM in Enterobacteriaceae in Sri Lanka.
Introduction: Guidelines for the selection of empirical antibiotics have been developed to improve patient outcomes and reduce unnecessary antibiotic use. We assessed the extent of adherence to the national guidelines for the selection of parenteral empirical antibiotics for three selected infections at a tertiary care center.
Methodology: A prospective cross-sectional study was conducted in medical and surgical wards of a tertiary care hospital in Sri Lanka.