Low-cost, local production of a safe and effective disinfectant for resource-constrained communities.

Improved hygiene depends on the accessibility and availability of effective disinfectant solutions. These disinfectant solutions are unavailable to many communities worldwide due to resource limitations, among other constraints. Safe and effective chlorine-based disinfectants can be produced via simple electrolysis of salt water, providing a low-cost and reliable option for on-site, local production of disinfectant solutions to improve sanitation and hygiene.

Evaluation of caries arresting potential of silver diamine fluoride and sodium fluoride varnish in primary molars: A randomized controlled trial.

Background: Caries management in the modern era has shifted away from the traditional surgical method toward a medical paradigm, which often includes fluoride therapy. Fluoride used in various forms has been proven to be effective in dental caries prevention. Silver diamine fluoride (SDF) and sodium fluoride (NaF) varnish are effective in arresting caries in primary molars.

Assessing inter and intra-variation in the characteristics of faecal sludge from Vadgaon Maval, Maharashtra: For better faecal sludge management in India.

Faecal Sludge (FS) produced in developing countries has become a significant source of water pollution. The optimal treatment of FS can lead to a sustainable economy. In India, the second phase of the open defecation free (ODF) initiative (energy recovery by providing city- or town-level centralised FS treatment plants) has begun from 2019 to sustain millions of toilets.

A critical review on sludge management from onsite sanitation systems: A knowledge to be revised in the current situation.

Access to safe excreta disposal is a basic human right and an essential element of human development. Developing countries (like India) have constructed millions of toilets with on-site sanitation technologies (OSTs). However, these OSTs lack the required management system for collection, transportation and disposal of Faecal Sludge (FS, sludge getting accumulated in OST), leading to considerable water and soil pollution.

Comprehensive bioanalytical multi-imaging by planar chromatography in situ combined with biological and biochemical assays highlights bioactive fatty acids in abelmosk.

The identification of the bioactivity of individual compounds in natural products is helpful to understand their therapeutic applications. Thus, a bioanalytical multi-imaging screening was developed and applied to 54 bark, leaf and seed extracts of Sri Lankan Abelmoschus moschatus (abelmosk) to find out the most bioactive individual compounds. The focus was laid on a comprehensive bioactivity profiling of its extracts.

Synthesis, in vitro and structural aspects of benzothiazole analogs as anti-oxidants and potential neuroprotective agents.

Catalase, an important antioxidant enzyme, is known to have a neuroprotective role against neurodegenerative disorder. Earlier study has focussed on benzothiazole-triazole hybrid molecules that are larger in size and molecular weight and inhibit the amyloid β (Aβ)-catalase interaction thus aid in neuroprotection. Here we have synthesized the novel benzothiazole molecules with low molecular weight using One-pot methodology and assayed the neuroprotective effects of the synthesized compounds in the U87 MG cell line under HO induced stressed condition and compared with other cell lines such as breast cancer (MCF-7) and macrophage (RAW-264.

Improvement in Obsessive-Compulsive Disorder Following Right Anterior Temporal Lobectomy and Amygdalohippocampectomy in a Patient with Refractory Temporal Lobe Epilepsy with Right Mesial Temporal Sclerosis.

There are reports of co-occurrence of obsessive-compulsive disorder (OCD) in patients with temporal lobe epilepsy (TLE). We present a report of a patient with refractory TLE due to hippocampal sclerosis with concomitant OCD on pharmacotherapy for both. She underwent surgery for standard anterior temporal lobectomy with amygdalohippocampectomy and reported improvement in obsessive-compulsive symptoms subsequently.

Pilocytic astrocytoma with spontaneous malignant transformation with intracranial and skeletal dissemination: case report and review of the literature.

Pilocytic astrocytoma is a benign low-grade tumor with a favorable prognosis. We present a 47-year-old- lady with a posterior fossa pilocytic astrocytoma who underwent surgical decompression. She developed multiple early local recurrences Along with malignant transformation of the cranial lesion she developed skeletal dissemination within a very short time frame.