Publications by authors named "Chance K"

Background: In light of the complex advances in neonatal intensive care units (NICU), it is essential that healthcare providers (HCPs) are equipped with the appropriate skills to effectively communicate between disciplines to provide safe, quality care. However, many HCPs acknowledge that they are not confident in their ability to communicate effectively with peers.

Purpose And Design: This study aimed to identify perceived barriers and facilitators of communication among HCPs in a NICU setting.

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Questions about how emissions are changing during the COVID-19 lockdown periods cannot be answered by observations of atmospheric trace gas concentrations alone, in part due to simultaneous changes in atmospheric transport, emissions, dynamics, photochemistry, and chemical feedback. A chemical transport model simulation benefiting from a multi-species inversion framework using well-characterized observations should differentiate those influences enabling to closely examine changes in emissions. Accordingly, we jointly constrain NO and VOC emissions using well-characterized TROPOspheric Monitoring Instrument (TROPOMI) HCHO and NO columns during the months of March, April, and May 2020 (lockdown) and 2019 (baseline).

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We present a new solar irradiance reference spectrum representative of solar minimum conditions between solar cycles 24 and 25. The Total and Spectral Solar Irradiance Sensor-1 (TSIS-1) Hybrid Solar Reference Spectrum (HSRS) is developed by applying a modified spectral ratio method to normalize very high spectral resolution solar line data to the absolute irradiance scale of the TSIS-1 Spectral Irradiance Monitor (SIM) and the CubeSat Compact SIM (CSIM). The high spectral resolution solar line data are the Air Force Geophysical Laboratory ultraviolet solar irradiance balloon observations, the ground-based Quality Assurance of Spectral Ultraviolet Measurements In Europe Fourier transform spectrometer solar irradiance observations, the Kitt Peak National Observatory solar transmittance atlas, and the semi-empirical Solar Pseudo-Transmittance Spectrum atlas.

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The world has seen an explosion in mobile device technology over the past decade, in addition to the impact that COVID-19 has placed on nursing education programs. More specifically, mobile devices have afforded users with endless possibilities. This upsurge in mobile technology has altered the way people use and interact with their device.

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The primary focus of this study is to understand the contribution from excess moisture from crop transpiration to the severity of a heat wave episode that hit the Midwestern U.S. from 16 to 20 July 2011.

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The purpose of this research project was to determine if using the Coping with Labor Algorithm would lead to changes in the perception of the intrapartum (IP) nurses' beliefs toward birth practices and frequency of labor support interventions. Twenty-three participants completed the preintervention survey, which included the IP Nurses' Belief Toward Birth Practice Scale and the Labor Support Scale. Following completion of the preintervention survey, participants received a copy of the Coping with Labor Algorithm and Toolkit and then began implementation of the Coping with Labor Algorithm.

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There is a great interest from global companies who are developing biosimilars to pursue interchangeability designation for commercialization of their products in the US. An interchangeability designation will not only allow the substitutability at the pharmacy level without the intervention of a health care provider but the first sponsor who is able to garner interchangeability designation will also receive 12 months of marketing exclusivity. This paper will highlight our current understanding of FDA expectations with regards to demonstrating interchangeability.

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Determining effective strategies for mitigating surface ozone (O) pollution requires knowledge of the relative ambient concentrations of its precursors, NO , and VOCs. The space-based tropospheric column ratio of formaldehyde to NO (FNR) has been used as an indicator to identify NO -limited versus NO -saturated O formation regimes. Quantitative use of this indicator ratio is subject to three major uncertainties: (1) the split between NO -limited and NO -saturated conditions may shift in space and time, (2) the ratio of the vertically integrated column may not represent the near-surface environment, and (3) satellite products contain errors.

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Article Synopsis
  • The study was a randomized, double-blind trial aimed at comparing the pharmacokinetics, safety, and immunogenicity of the adalimumab biosimilar M923 with two reference products, US Humira and EU Humira, using a single 40-mg dose.
  • Results showed that M923 demonstrated pharmacokinetic equivalence to both reference products, with geometric least squares means ratios for key endpoints (C_max, AUC_inf, AUC_336) falling within the acceptable range of 80%-125%.
  • Adverse events were similar across all groups, mostly mild or moderate, and confirmed antidrug antibody response rates were also comparable, indicating that M923 is safe and tolerable like its
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Article Synopsis
  • Formaldehyde is identified as the primary carcinogen in outdoor air among 187 hazardous pollutants, with concerns about limited EPA monitoring and data collection.
  • Satellite data from 2005-2016 is utilized to estimate HCHO concentrations across the U.S., showing good agreement with urban observations but lower than EPA annual averages, leading to cancer risk estimates for 6,600-12,500 individuals.
  • The major source of outdoor HCHO is biogenic isoprene oxidation, and reducing nitrogen oxide emissions can significantly lower HCHO levels, providing a dual benefit of improving ozone quality and reducing cancer risks.
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There is a great interest from companies located in Asia to bring biosimilars into Western markets such as the United States, European Union, and Canada, because these are lucrative markets with patents expiring or close to expiry for many originator biologics. Although many sponsors are successfully developing and marketing biosimilars for their own countries, there is an increasing interest among companies in China, Hong Kong, India, Korea, Taiwan, and other Asian countries in targeting markets in the West. As a result, there is widespread interest among these companies in learning about the requirements for regulatory approval in Western countries.

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TEMPO was selected in 2012 by NASA as the first Earth Venture Instrument, for launch between 2018 and 2021. It will measure atmospheric pollution for greater North America from space using ultraviolet and visible spectroscopy. TEMPO observes from Mexico City, Cuba, and the Bahamas to the Canadian oil sands, and from the Atlantic to the Pacific, hourly and at high spatial resolution (~2.

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This article examines the current landscape of biosimilar development in rheumatology. As misperceptions about biosimilars exist regarding their comparability to the reference products for clinical use, we review the development paradigm with the goal of improving rheumatologists' understanding of the rigor with which biosimilars are developed. With an emphasis on European Union and US markets, it gives an overview of some of the challenges and issues related to biosimilar development that need to be considered by rheumatologists in this increasingly growing therapeutic space.

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Formaldehyde (HCHO) column data from satellites are widely used as a proxy for emissions of volatile organic compounds (VOCs) but validation of the data has been extremely limited. Here we use highly accurate HCHO aircraft observations from the NASA SEACRS campaign over the Southeast US in August-September 2013 to validate and intercompare six retrievals of HCHO columns from four different satellite instruments (OMI, GOME2A, GOME2B and OMPS) and three different research groups. The GEOS-Chem chemical transport model is used as a common intercomparison platform.

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Background: There is little evidence to compare the effectiveness of large collaborative quality improvement versus individual local projects.

Methods: This was a prospective pre-post intervention study of neonatal resuscitation practice, comparing 3 groups of nonrandomized hospitals in the California Perinatal Quality Care Collaborative: (1) collaborative, hospitals working together through face-to-face meetings, webcasts, electronic mailing list, and data sharing; (2) individual, hospitals working independently; and (3) nonparticipant hospitals. The collaborative and individual arms participated in improvement activities, focusing on reducing hypothermia and invasive ventilatory support.

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OMI HCHO is validated over the continental US (CONUS), and used to analyze regional sources in Northeast Asia (NA) and Southeast Asia (SA). OMI HCHO Version 2.0 data show unrealistic trends, which prompted the production of a corrected OMI HCHO data set.

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Dens evaginatus is a rare dental anomaly that occurs during tooth development and results in an abnormal protrusion from the occlusal surface of the affected tooth, often in the area of the central groove between the buccal and lingual cusps. Of clinical importance to the orthodontist is that these occlusal tubercles fracture easily or can be worn away, resulting in direct pulp exposure in a noncarious tooth. This can cause severe complications, including loss of tooth vitality, facial infection in the form of an abscess or cellulitis, or osteomyelitis of the jaw.

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Objective: To evaluate a multihospital collaborative designed to increase breast milk feeding in premature infants.

Methods: Eleven NICUs in the California Perinatal Quality of Care Collaborative participated in an Institute for Healthcare Improvement-style collaborative to increase NICU breast milk feeding rates. Multiple interventions were recommended with participating sites implementing a self-selected combination of these interventions.

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Purpose: The purpose of this survey was to assess and compare the attitudes of pediatric and general dentists regarding treatment planning of indirect pulp therapy (IPT) in primary teeth.

Methods: A 15-item electronic survey was sent to 3,883 general dentists and 3,691 pediatric dentists nation-wide to assess their knowledge and attitudes regarding the treatment planning of IPT through the presentation of clinical scenarios.

Results: Of the 7,574 electronic surveys distributed, 1,259 (17%) were completed.

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We use 2005-2009 satellite observations of formaldehyde (HCHO) columns from the OMI instrument to infer biogenic isoprene emissions at monthly 1 × 1° resolution over the African continent. Our work includes new approaches to remove biomass burning influences using OMI absorbing aerosol optical depth data (to account for transport of fire plumes) and anthropogenic influences using AATSR satellite data for persistent small-flame fires (gas flaring). The resulting biogenic HCHO columns (Ω) from OMI follow closely the distribution of vegetation patterns in Africa.

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We present results from the OP3 campaign in Sabah during 2008 that allow us to study the impact of local emission changes over Borneo on atmospheric composition at the regional and wider scale. OP3 constituent data provide an important constraint on model performance. Treatment of boundary layer processes is highlighted as an important area of model uncertainty.

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[1] We combine aircraft measurements (Second Texas Air Quality Study, Megacity Initiative: Local and Global Research Observations, Intercontinental Chemical Transport Experiment: Phase B) over the United States, Mexico, and the Pacific with a 3-D model (GEOS-Chem) to evaluate formaldehyde column (Ω) retrievals from the Ozone Monitoring Instrument (OMI) and assess the information they provide on HCHO across local to regional scales and urban to background regimes. OMI Ω correlates well with columns derived from aircraft measurements and GEOS-Chem ( = 0.80).

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Objective: The objective of this study was to reduce central line-associated blood stream infections (CLABSIs) among 13 collaborating regional neonatal intensive care units by 25%. We tested the hypothesis that change could be attributed to the quality improvement collaborative by testing for 'special cause' variation.

Study Design: Our prevention project included five features: (1) leadership commitment, (2) potentially best practices, (3) collaborative processes, (4) audit and feedback tools and (5) quality improvement techniques.

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Purpose: To evaluate the time needed to remove a glass reinforced fiber post versus a titanium post.

Methods: 40 extracted anterior teeth were mounted in acrylic blocks then treated endodontically. They were randomly assigned to three groups.

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Space-borne column measurements of formaldehyde (HCHO), a high-yield oxidation product of volatile organic compounds (VOCs), represent important constraints for quantifying net regional fluxes of VOCs. Here, we interpret observed distributions of HCHO columns from the Global Ozone Monitoring Experiment (GOME) over tropical South America during 1997-2001. We present the first comparison of year-long in situ isoprene concentrations and fire-free GOME HCHO columns over a tropical ecosystem.

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