Isolated and Sporadic Human Mesiodens Is Associated with a Synonymous Variant in the Gene.

The purpose of this study was to use targeted next-generation sequencing (NGS) to identify possible causative genes for isolated and sporadic human mesiodens. The targeted panel consisted of 101 target genes related to tooth development. NGS of this panel was initially performed on a discovery set (39 cases and 27 controls); association tests were performed after genotyping of nine selected variants in a validation set (57 cases and 56 controls).

Color changes of ceramic veneers following glazing with respect to their composition.

Purpose: The purpose of this study was to compare the translucency and color changes of ceramic laminate veneers of different composition following glazing process.

Materials And Methods: 10 mm × 10 mm square specimens of 0.6 mm and 1.

Managing the behavior of a patient with autism by sedation via submucosal route during dental treatment.

In sedation via the submucosal route, the drug is administered through the maxillary buccal submucosa. It is time saving, effective, and safe. Patients with autism, a mental disorder, often find it hard to make relationships with other people.