[The prevention of ulcer relapses in patients with an ulcerative anamnesis in clinical and endoscopic remission following the eradication of Helicobacter infection of the gastric mucosa].

The contemporary scientific consensus recommends treatment of the Helicobacter pylori infection in patients with history of peptic ulcer independently of the stage of activity. The object of the study was to confirm the necessity for treatment of Helicobacter pylori infection in patients with duodenal peptic ulcer in stage of clinical and endoscopic remission. To investigation were submitted 55 patients divided into in two groups--30 patients treated with triple medicinal combination of metronidasol 2 x 20 mg, amoxycillin 2 x 1000 mg and metronidasol 3 x 500 mg for 7 days.

[The treatment of reflux esophagitis in patients with a Helicobacter infection of the gastric mucosa].

Among the pathogenetic mechanisms for the occurrence of gastroesophageal reflux disease, Helicobacter pylori infection is indicated. The conclusions are absolutely opposite. The object of our work was to assume ex juvantibus to what extent the eradication of the Helicobacter pylori infection would accelerate the healing of patients with reflux oesophagitis and would reduce the number of relapses.

[The anesthesiological-resuscitation and surgical problems in a female patient with an adrenal cortex carcinoma].

A patient has been observed with virilizing cancer of the adrenal cortex. Anesthesiologic-resuscitation and operative problems are discussed. The importance of corticosteroid substitutional treatment is emphasized.

[Our experience of treating urological infections with a single dose of gentamycin].

31 patients with a urological infection caused by a bacterial strain susceptible to gentamycin were treated by a single injection of 240 mg of gentamycin. 11 patients (35.5%) fully recovered, the infection was eliminated and the clinical symptoms and signs disappeared.

[A more efficient method of gastric intubation].

A self time-regulating aspiration device is presented. The device is a combination of a buffer container and a gastric tube and provides improved gastric intubation, gives more accurate results, has a high reliability of exploitation and there is no need of constant personal attendance.

[Comparative in vitro research on 2 new antacid combinations--Ulsan and Ulsan D].

Two new antacid combinations--Ulsan and Ulsan D with high acid-neutralizing properties, produced by original Bulgarian techniques are presented. They exceed in acid-binding and acid-reducing properties the drugs now in use: Antiacid, Neutracid, Almagel, Alcid V, Maaloxan, Gelusil-Lac.

[Acute interstitial nephritis following the use of gentamycin].

The authors describe a patient that developed acute interstitial nephritis after gentamycin administration. The disease progressed with general lassitude, subfebrile temperature, oliguria, and increased nitrogen bodies in blood. After a short oliguric stage, polyuria followed and the renal function was completely normalized one month after the onset of the disease.

[Method for determining the acid-reducing capacity of antacid preparations].

A method is proposed for the determination of acid-binding ability of antacids, enabling the automatic reading of pH changes. Changes are provided for work with original gastric juice. The method allows the determination of individual dosage of antacid for each patient.

[Treatment with Pharmachim's Chlophazolin of hypertension and symptomatic hypertonia].

A total of 127 patients with arterial hypertension--64 with symptomatic and 63 with essential, were treated with chlophazolin "Pharmachim" at the Clinic of Therapy of Internal Diseases and Clinical Pharmacology for a period of one year. The drug was used alone in part of the patients and in the rest--in combination with other drugs. Satisfactory effect on the clinical symptoms and the level of blood pressure was attained in all patients treated and in only a small part of them diuretics and beta-blockers were necessary so as to attain better effect in coping with the arterial hypertension.

[Causative agents of urologic infections and their sensitivity to the most frequently used antibiotics and chemotherapeutic agents (data from the Clinic for the Therapy of Internal Diseases and Clinical Pharmacology for 1984)].

The causative agents of uroinfections were studied among the patients at the Clinic of therapy of internal diseases and clinical pharmacology during 1984. Significant bacteriuria was established in 279 out of 485 patients, with 1475 urine inoculations performed, 14 with mixed flora. The highest is the share of E.

[Mycoplasma as the causative agent of kidney infections].

A total of 185 patients were investigated for M. hominis and mycoplasmal infection was established in 28 patients. In 2 of the patients mixed infection with E.

[Clinical trial of drugs for treating urological infections--pipemidic acid].

A method was elaborated for clinical trial of pharmaceuticals for the treatment of infections of kidneys and urinary ducts. The main requirements are as follows: definitive diagnostic criteria for urological infection, monotherapy, systematic control for the drug intake, precisely formulated indices for assessment of the effect, strict follow-up of adverse and toxic effects. The effect was assessed according to a three-stage scale: very good, good and poor, consideration given not only to the clinical and laboratory indices but to adverse effects as well.

[Treatment of duodenal ulcer with herbazol].

A total of 61 patients were treated - 30 with Herbazol , 16 with placebo and 15 with Biomet . Pain and dyspeptic complaints disappeared in a high percentage of the patients after 25-day treatment with the phytopreparation Herbazol , with no statistical significance of the differences with placebo and Biomet . The preparation Herbazol has the tendency to reduce the basal salt-acid production of the stomach and reduces the stimulated one with a statistical significance.

[Comparative studies of the therapeutic effect of a herbazol preparation with and without an antacid component in duodenal peptic ulcer patients].

A total of 64 patients were treated - 30 with Herbazol A (with antacid component), 18 with Herbacid B (without antacid component) and 16 - with placebo. Herbazol A was established to eliminate the subjective pain and dyspeptic complaints a little earlier as compared with Herbazol B. Both preparations have the same action as regards the effect on hydrochloric acid gastric secretion and the healing of the ulcer niché.

[Treatment of chronic colitis with an herbal combination of Taraxacum officinale, Hipericum perforatum, Melissa officinaliss, Calendula officinalis and Foeniculum vulgare].

Twenty four patients with chronic non-specific colitis were treated with a herb combination. As a result from the treatment, the spontaneous and palpable pains along the large intestine disappeared in 95.83 per cent of the patients by the 15th day of their admission to the clinic.

[Use of an herbal combination with laxative action on duodenal peptic ulcer and gastroduodenitis patients with a concomitant obstipation syndrome].

Thirty two patients were treated--19 with duodenal ulcer and 19 with gastroduodenitis, all of them with concomitant obstipation syndrome. The patients were treated with a combination of Symphitum officinalis and Calendula officinales form the main disease. The obstipation syndrome was treated with a combination of Rhamus frangula, Citrus aurantium, Carum carvi.

[Treanntment of duodenal ulcers and gastroduodenitis with a herbal combination of Symphitum officinalis and Calendula officinalis with and without antacids].

A total of 170 patients were treated--137 only with the herb combination (78 with duodenal ulcer and 59 with gastroduodenitis), 33--with the herb combination together with antacid (21 with duodenal ulcer and 12 with gastroduodenitis). As a result from the treatment, the spontaneous pains disappeared in 90 per cent of the patients--in the group with and in the group without antacid, the dyspeptic complaints faded in over 85 per cent but in the patients, treated with herbs and antacid the mentioned complaints disappeared several days earlier. The palpitation pains, in both groups, disappeared in more than 90 per cent of the patients within the same time.