Genome-based analyses indicate that subsp. and subsp. do not merit separation to subspecies status.

The species currently comprises two subspecies, viz. subsp. and subsp.

Surfactant-Mediated Solubilization of Magnetically Separable Nanocatalysts for the Oxidation of Alcohols.

Cetrimonium bromide (CTAB)-coated water disperse magnetically separable nanocatalysts CTAB/FeO@dopa@ML (M = Fe or Mn, L = cyclohexane-1,2-diylbis(azanylylidene)bis(methanylylidene)bis(2,4-diXphenol; X = Cl, Br, and I) have been synthesized using a simple synthetic strategy. This approach provides a new fruitful strategy to reduce the leaching of the active metal complex from the catalyst surface to the aqueous media. The synthesized catalysts have been found to be excellent for oxidation of alcohols in aqueous medium at room temperature.

Divagations about the periodic table: Boolean hypercube and quantum similarity connections.

In this study, several simple aspects associated with the periodic table (PT) of the elements are commented. First, the connection of the PT with the structure of a seven-dimensional Boolean hypercube leads afterward to discuss the nature of those PT elements bearing prime atomic numbers. Second, the use of quantum similarity (QS) to obtain an alternative insight on the PT element relations will be also developed.

Estrogen Receptor β2 Oversees Germ Cell Maintenance and Gonadal Sex Differentiation in Medaka, Oryzias latipes.

In vertebrates, estrogen receptors are essential for estrogen-associated early gonadal sex development. Our previous studies revealed sexual dimorphic expression of estrogen receptor β2 (ERβ2) during embryogenesis of medaka, and here we investigated the functional importance of ERβ2 in female gonad development and maintenance using a transgenerational ERβ2-knockdown (ERβ2-KD) line and ERβ2-null mutants. We found that ERβ2 reduction favored male-biased gene transcription, suppressed female-responsive gene expression, and affected SDF1a and CXCR4b co-assisted chemotactic primordial germ cell (PGC) migration.

The Candida albicans biofilm gene circuit modulated at the chromatin level by a recent molecular histone innovation.

Histone H3 and its variants regulate gene expression but the latter are absent in most ascomycetous fungi. Here, we report the identification of a variant histone H3, which we have designated H3VCTG because of its exclusive presence in the CTG clade of ascomycetes, including Candida albicans, a human pathogen. C.

Magnetocaloric effect as a signature of quantum level-crossing for a spin-gapped system.

Recent research dealing with magnetocaloric effect (MCE) study of antiferromagnetic (AFM) low dimensional spin systems have revealed a number of fascinating ground-state crossover characteristics upon application of external magnetic field. Herein, through MCE investigation we have explored field-induced quantum level-crossing characteristics of one such spin system: [Formula: see text] (NCP), an AFM spin 1/2 dimer. Experimental magnetization and specific heat data are presented and the data have been employed to evaluate entropy, magnetic energy and magnetocaloric properties.

Near-ubiquitous presence of a vancomycin-resistant ST117/CT71/B -clone in the Rhine-Main metropolitan area of Germany.

Whole-genome sequencing analysis of Vancomycin-resistant isolates from the Frankfurt metropolitan region revealed that 78/94 isolates were MLST type ST117, cgMLST complex type CT71 with a common B chromosomal insertion site. This indicates circulation of a single VRE clone in a catchment area of 5,000-km with 3 million inhabitants.

Glutathione deficiency-elicited reprogramming of hepatic metabolism protects against alcohol-induced steatosis.

Depletion of glutathione (GSH) is considered a critical pathogenic event promoting alcohol-induced lipotoxicity. We recently show that systemic GSH deficiency in mice harboring a global disruption of the glutamate-cysteine ligase modifier subunit (Gclm) gene confers protection against alcohol-induced steatosis. While several molecular pathways have been linked to the observed hepatic protection, including nuclear factor erythroid 2-related factor 2 and AMP-activated protein kinase pathways, the precise mechanisms are yet to be defined.

Light controlled cell-to-cell adhesion and chemical communication in minimal synthetic cells.

Decorating GUVs, used as minimal synthetic cell models, with photoswitchable proteins allows controlling the adhesion between them and their assembly into multicellular structures with light. Thereby, the chemical communication between a sender and a receiver GUV, which strongly depends on their spatial proximity, can also be photoregulated.

Record-high thermal stability achieved in a novel single-component all-organic ferroelectric crystal exhibiting polymorphism.

Traditionally, lead and heavy metal containing inorganic oxides dominate the area of ferroelectricity. Although, recently, lightweight non-toxic organic ferroelectrics have emerged as excellent alternatives, achieving higher temperature up to which the ferroelectric phase can persist has remained a challenge. Moreover, only a few of those are single-component molecular ferroelectrics and were discovered upon revisiting their crystal structures.

Dysautonomia in Guillain-Barré Syndrome: Prevalence, Clinical Spectrum, and Outcomes.

Background: Guillain-Barré syndrome (GBS), when severe, involves the autonomic nervous system; our objective was to assess the spectrum and predictors of dysautonomia, and how it may impact functional outcomes.

Methods: A retrospective review of patients admitted to the Mayo Clinic in Rochester, MN between January 1, 2000, and December 31, 2017, with GBS and dysautonomia was performed. Demographics, comorbidities, parameters of dysautonomia, clinical course, GBS disability score, and Erasmus GBS Outcome Score (EGOS) at discharge were recorded.

Seeking Maxwell's Demon in a non-reciprocal quantum ring.

A non-reciprocal quantum ring, where one arm of the ring contains the Rashba spin-orbit interaction but not in the other arm, is found to posses very unique electronic properties. In this ring the Aharonov-Bohm oscillations are totally absent. That is because in a magnetic field the electron stays in the non-Rashba arm, while it resides in the Rashba arm for zero (or negative) magnetic field.

Construing the Biochemical and Molecular Mechanism Underlying the and Chemotherapeutic Efficacy of Ruthenium-Baicalein Complex in Colon Cancer.

In pursuit of a novel approach in colon cancer therapy, we explored the ability of ruthenium baicalein complex to eradicate colon cancer by efficiently targeting various apoptotic pathways on human colon cancer cell line and on a DMH and DSS induced murine model of colorectal cancer. In this study, we provide direct proof of the chemotherapeutic potential of the ruthenium baicalein complex by activating p-53 dependent intrinsic apoptosis and modulating the AKT/mTOR and WNT/β- catenin pathways. The ruthenium baicalein complex was synthesized and its characterizations were accomplished through various spectroscopic techniques followed by assessment of antioxidant potential by DPPH, FRAP, and ABTS methods.

Sensory perception of dead conspecifics induces aversive cues and modulates lifespan through serotonin in Drosophila.

Sensory perception modulates health and aging across taxa. Understanding the nature of relevant cues and the mechanisms underlying their action may lead to novel interventions that improve the length and quality of life. We found that in the vinegar fly, Drosophila melanogaster, exposure to dead conspecifics in the environment induced cues that were aversive to other flies, modulated physiology, and impaired longevity.

Bacterial Outer Membrane Vesicles (OMVs)-based Dual Vaccine for Influenza A H1N1 Virus and MERS-CoV.

Vaccination is the most functional medical intervention to prophylactically control severe diseases caused by human-to-human or animal-to-human transmissible viral pathogens. Annually, seasonal influenza epidemics attack human populations leading to 290-650 thousand deaths/year worldwide. Recently, a novel Middle East Respiratory Syndrome Coronavirus emerged.

The Clinical Spectrum of New-Onset Status Epilepticus.

Objectives: There is a paucity of data on patients with new-onset status epilepticus in patients without a prior history of epilepsy; we aimed to describe clinical characteristics and assess variables predictive of outcomes.

Design: Retrospective cohort.

Setting: Quaternary academic medical center.

Weaning from antiseizure drugs after new onset status epilepticus.

Objective: In patients with status epilepticus (SE) without prior epilepsy, there are limited data on the safety of discontinuing antiseizure drugs (ASDs) after seizure control. We aimed to describe seizure recurrence when weaning from ASDs following new onset SE (NOSE).

Methods: Retrospective review of adult patients with NOSE admitted to Mayo Clinic, Rochester, Minnesota between January 1, 1990 and December 31, 2015 was performed.

Sequential organ failure assessment score is an excellent operationalization of disease severity of adult patients with hospitalized community acquired pneumonia - results from the prospective observational PROGRESS study.

Background: CAP (Community acquired pneumonia) is frequent, with a high mortality rate and a high burden on health care systems. Development of predictive biomarkers, new therapeutic concepts, and epidemiologic research require a valid, reproducible, and quantitative measure describing CAP severity.

Methods: Using time series data of 1532 patients enrolled in the PROGRESS study, we compared putative measures of CAP severity for their utility as an operationalization.

Variable Significance of Brain MRI Findings in Infective Endocarditis and Its Effect on Surgical Decisions.

Objective: To determine how brain magnetic resonance imaging (MRI) findings impact clinical outcomes in patients with infective endocarditis (IE) and to propose a management algorithm for patients with neurologic symptoms who are candidates for valve surgery (VS).

Patients And Methods: Data from our center were retrospectively reviewed for patients hospitalized with IE between January 1, 2007, and December 31, 2014. Outcomes were postoperative intracerebral hemorrhage (ICH), 6-month mortality, and functional outcome at last follow-up as described by the modified Rankin Scale (mRS) score.

Modulations of ν and ν Stretching Frequencies of Difluoroacetic Acid with Internal Rotation of CHF Rotor: A Combined Vapor Phase and Matrix Isolation Infrared Spectroscopy Study.

Mid-infrared spectra of difluoroacetic acid (DFAA) have been measured by isolating the molecule in argon and nitrogen matrices at 8 K and also in the vapor phase at room temperature. In argon matrix, the O-H stretching fundamental (ν) of -COOH group appears as a doublet with band maxima at 3554 and 3558 cm, and a similar doublet for C═O stretching fundamental appears at 1800 and 1810 cm. In the vapor phase, the ν transition is featured with multiple peaks, and the observed band shape has been deconvoluted as superposition of two transitions both having A-type rotational band contours.

Draft Genome Sequence of Listeria monocytogenes CIIMS-NV-3, a Strain Isolated from Vaginal Discharge of a Woman from Central India.

We present here the draft genome sequence of Listeria monocytogenes CIIMS-NV-3, a serovar 4b strain isolated from the vaginal swab of a female patient from central India. The availability of this genome may provide useful information on virulence characteristics for comparative genomic analysis.

Mass Spectrometry-Based Profiling of Metabolites in Human Biofluids.

Cancer poses a daunting challenge to researchers and clinicians alike. Early diagnosis, accurate prognosis, and prediction of therapeutic response remain elusive in most types of cancer. In addition, lacunae in our understanding of cancer biology continue to hinder advancement of therapeutic strategies.

Anion-mediated bio-relevant catalytic activity of dinuclear nickel(ii) complexes derived from an end-off compartmental ligand.

Four dinuclear nickel(ii) complexes, namely [Ni4(L)2(H2O)8(μ2-H2O)2](NO3)6(H2O)6 (1), [Ni2(L)Cl2(μ-Cl)(CH3OH)] (2), [Ni2(L)(OAc)2(H2O)2]Br (3) and [Ni2(L)(H2O)4(μ2-OH)] (H2O)X(I)X (4), have been synthesized using a template synthesis technique by adding nickel(ii) salts (nitrate/chloride/bromide/iodide) to the N4O donor end-off compartmental ligand (HL) obtained via the condensation of 2-(2-pyridyl)ethylamine and 2,6-diformyl-4-isopropyl phenol in methanol. All complexes were characterized with the help of typical physicochemical techniques, and their solid-state structures were assigned from single crystal X-ray analysis. The variable temperature magnetic study reveals that the two nickel centers are antiferromagnetically coupled with J values ranging from -5 to -15 cm-1 in the complexes.