Publications by authors named "Chak Lam Chan"
Res Microbiol
November 2018
Article Synopsis
- The PACE family of transport proteins, recently identified in proteobacteria, plays a crucial role in antibiotic resistance against common disinfectants and is found in many significant Gram-negative pathogens.
- These proteins are thought to serve essential functions beyond just resistance to biocides and are typically conserved in bacterial core genomes rather than on mobile genetic elements.
- Although structural details are lacking, PACE proteins show strong conservation in their amino acid sequences, suggesting they arose from an ancestral protein and warrant further study due to their importance in drug resistance.
