Publications by authors named "Chaiyakunapruk N"
Article Synopsis
- The review examined cost-effectiveness analyses of new adult pneumococcal vaccines (PCV15 and PCV20) across different countries.
- Most studies found that PCV20 offered cost savings or was more cost-effective than older vaccination strategies in high-income countries.
- Assumptions about vaccine effectiveness, duration of protection, and herd immunity effects varied, with most studies considered low-risk for bias.
Background: Globally, herpes simplex virus (HSV)-2 and -1 infections contribute to a large disease burden, but their full economic consequences remain unclear. This study aims to estimate the global economic impact of genital HSV-2 and HSV-1 infection and its consequences for people with genital ulcer disease, neonatal herpes, and human immunodeficiency virus (HIV) infection attributable to HSV-2.
Methods: Using a societal perspective, the economic burden was calculated at the country level and presented by World Health Organization (WHO) regions and World-Bank income levels.
Background: Although innovation generally provides measurable improvements in disease characteristics and patient survival, some benefits can remain unclear. This study aimed to investigate patient and healthcare provider (HCP) preferences for the innovative attributes of multiple myeloma (MM) treatments.
Methods: A cross-sectional, web-based, discrete choice experiment (DCE) survey was conducted among 200 patients with MM and 30 HCPs of patients with MM in the USA.
Article Synopsis
- This systematic review investigates the cost-effectiveness of brexu-cel, a treatment for mantle cell lymphoma and acute lymphoblastic leukemia, across different countries.
- A thorough search was conducted, leading to the review of 149 records, of which 22 were fully analyzed, resulting in five articles and seven health technology assessment (HTA) reports meeting the criteria.
- The findings indicate that brexu-cel is deemed cost-effective in several studies, particularly in Scotland, but some HTA agencies expressed doubts about its cost-effectiveness for certain conditions.
Gout is the most common inflammatory arthritis, affecting approximately 5.1% of adults in the United States (US) population. Gout is a metabolic and autoinflammatory disease.
View Article and Find Full Text PDFBackground: Alcohol is linked to various cancers. While many studies have focused on developed countries, the burden of alcohol-related cancers in developing countries remains underexplored.
Methods: We analyzed data from the Global Burden of Disease Study (2000-2019) to assess mortality and disability-adjusted life years (DALYs) from alcohol-related cancers in low and low-to-middle sociodemographic index (SDI) countries.
Background: Poor adherence to chronic cardiovascular treatments can impede targeted clinical outcomes. This study estimates the potential benefits of improving adherence among patients with cardiovascular disease requiring secondary prevention in Mexico, Thailand, and China.
Methods And Results: We performed Markov model simulation for patients with cardiovascular disease in 3 countries from health care and societal perspectives over a lifetime horizon.
Background: Pharmacovigilance is essential for patient safety, but underreporting adverse drug reactions (ADRs) is a global challenge.
Objectives: This review evaluated the effectiveness of strategies for enhancing ADR reporting by healthcare professionals (HCPs).
Methods: This systematic review was conducted following the Cochrane and the PRISMA guidelines.
Importance: The US Department of Veterans Affairs (VA) partners with community organizations (grantees) across the US to provide temporary financial assistance (TFA) to vulnerable veterans through the Supportive Services for Veteran Families (SSVF) program. The goal of TFA for housing-related expenses is to prevent homelessness or to quickly house those who have become homeless.
Objective: To assess the cost-effectiveness of the SSVF program with TFA vs without TFA as an intervention for veterans who are experiencing housing insecurity.
Real-World Assessment of Economic and Clinical Outcomes in Thai Patients With Respiratory Syncytial Virus Infection Across Age Groups: A Retrospective Cohort Analysis.
Influenza Other Respir Viruses
November 2024
Article Synopsis
- RSV causes significant respiratory infections in Thailand, prompting a study to evaluate its clinical and economic impacts across different age groups from 2014 to 2021.* -
- The study found 2122 RSV-positive patients, with hospitalization costs ranging from approximately USD 780 for children under 2 to USD 2231 for adults over 65; hospitalization rates and costs increased with age and existing health issues.* -
- While younger children faced the highest overall burden, older adults showed worse health outcomes, highlighting the need for targeted vaccination programs to address these challenges effectively.*
Objective: We aimed to synthesize clinical and economic outcomes of rapid start versus nonrapid antiretroviral therapy (ART) in people with HIV (PWH) in real-world settings.
Methods: A search was conducted in PubMed, Embase, Web of Science, and ProQuest from January 2017 to January 2023, supplementing a previous search by Ford et al . in 2018.
Perceptions of patients and caregivers toward the management of rare disease in Malaysia: a qualitative research study.
Int J Technol Assess Health Care
October 2024
Objective: The management of rare diseases is rarely addressed among policymakers and public communities. It is hindered by the lack of information on its epidemiology and burden, especially from the perspective of patients and families with rare diseases. This study aims to understand the perceptions of rare disease patients and their families in the management of rare diseases in Malaysia.
View Article and Find Full Text PDFPsychological interventions are complex in nature and have been shown to benefit various clinical outcomes. Gaining insight into current practices would help identify specific aspects that need improvement to enhance the quality of network meta-analysis (NMA) in this field. This scoping review aimed to explore methodological approaches in the NMA of psychological interventions.
View Article and Find Full Text PDFBackground: (. ) is a common pathogen of community-acquired pneumonia. Interleukin-17 (IL-17) plays a role in host defense and contributes to disease severity in infection.
View Article and Find Full Text PDFIntroduction: The treatment of type 2 diabetes requires multidimensional management, with medication adherence a crucial aspect of diabetes control. However, recent rigorous estimates of adherence to oral antidiabetic drugs (OAD) are lacking. The objective of this study is to determine the prevalence of adherence to OAD in type 2 diabetes patients.
View Article and Find Full Text PDFNearly all patients with type 1 diabetes and 20-30 percent of patients with type 2 diabetes use insulin to manage glycemic control. Approximately one-quarter of patients who use insulin report underuse because of cost. In response, more than twenty states have implemented monthly caps on insulin out-of-pocket spending, ranging from $25 to $100.
View Article and Find Full Text PDFBackground And Aims: Inflammatory Bowel Disease (IBD) represents a significant health threat worldwide. However, there are deficiencies in large-scale epidemiological research focusing on these issues, especially among young women. We aim to examine the trend of IBD in young females globally.
View Article and Find Full Text PDFBackground: The management of warfarin therapy presents clinical challenges due to its narrow therapeutic index. We aimed to evaluate the comparative effectiveness of different management strategies in patients using warfarin.
Methods: PubMed, Embase, Cochrane CENTRAL, CINAHL, and EBSCO Open Dissertation were searched from inception to 8 May 2024.
Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are chronic, highly prevalent viral infections that cause significant morbidity around the world. HSV-2 is sexually transmitted and is the leading cause of genital ulcer disease (GUD). It also increases the risk of HIV acquisition, fueling the HIV epidemic.
View Article and Find Full Text PDFArticle Synopsis
- - CDI is a widespread healthcare-associated infection that significantly affects the elderly, posing serious health and economic issues, yet detailed data on its impact are scarce.
- - Using data from the Global Burden of Disease Study 2019, the analysis from 2000 to 2019 showed CDI resulted in about 18,181 deaths and 252,709 disability-adjusted life years (DALYs) among older adults, with the Americas facing the highest burden.
- - The findings highlight the urgent need for specialized public health strategies to address the rising CDI rates, particularly in high-sociodemographic index (SDI) regions and the Americas.
Unlabelled: During COVID-19 in the US, social determinants of health (SDH) have driven health disparities. However, the use of SDH in COVID-19 vaccine modeling is unclear. This review aimed to summarize the current landscape of incorporating SDH into COVID-19 vaccine transmission modeling in the US.
View Article and Find Full Text PDFBackground: With advancements in CF drug development, people with cystic fibrosis (PwCF) now take a median of seven medications daily, increasing treatment complexity, risk of drug therapy problems (DTPs), and interference with treatment goals. Given that some of these DTPs can be prevented with preemptive pharmacogenetic testing, the overall goal of this study was to test the clinical utility of a multi-gene pharmacogenetics (PGx) panel in potentially reducing DTPs in PwCF.
Methods: A population based retrospective study of patients with CF was conducted at the University of Utah Health Care System.
Introduction: We evaluated the relative effects of newer versus older medications for neonatal conditions and trends in margin of superiority across generations.
Materials And Methods: We assessed network meta-analyses (NMAs) on neonatal pharmacological interventions identified from MEDLINE, Cochrane, and PROSPERO. Interventions were chronologically arranged based on the earliest study and compared for their effects against placebo or no treatment and their immediate predecessor.
Article Synopsis
- Alcohol consumption is linked to significant health issues worldwide, including alcohol use disorder (AUD), liver disease, and heart disease, contributing to increased disability and mortality rates, especially among lower socio-economic groups.
- In 2019, AUD had the highest rate of disability-adjusted life years, with liver disease and alcohol-induced heart problems also notable, although some rates showed slight declines.
- The burden of alcohol-related health complications is rising particularly in low and low-middle income countries, highlighting an urgent need for effective public health strategies to tackle these challenges.