Indian J Endocrinol Metab
January 2018
Context: To find a single time point during clonidine stimulation test (CST), with highest diagnostic value to rule out growth hormone deficiency (GHD).
Settings And Design: This is a retrospective study of 79 CSTs carried out in a tertiary care center in India.
Materials And Methods: A cohort of 79 children with unexplained short stature was divided into two groups: GHD and non-GHD.
Objective: To study genotype-phenotype spectrum of triple A syndrome (TAS).
Methods: Retrospective chart analysis of Indian TAS patients (cohort 1, = 8) and review of genotyped TAS cases reported in world literature (cohort 2, = 133, 68 publications).
Results: Median age at presentation was 4.
Macroprolactinomas are the most common functional pituitary tumours. Hypotheses proposed to explain predominance of large tumours in males are: i) diagnostic delay, as hyperprolactinaemia remains under recognised in males and ii) gender-specific difference in tumour proliferation indices. Our study objectives are to compare gender differences in clinical, biochemical, radiological features, management outcomes and cabergoline responsiveness in macroprolactinomas.
View Article and Find Full Text PDFObjective: Variable efficacy of pituitary radiotherapy in acromegaly is reported. Here we sought to assess the efficacy of high-precision conformal fractionated radiotherapy (CRT) in patients with acromegaly after failed TSS.
Methods: A retrospective analysis was conducted a in tertiary care referral center between 1999 to 2013 on 36 acromegaly patients (M: 16, F: 20; median age: 36.