Dataset of in-situ coaxial monitoring and print's cross-section images by Direct Energy Deposition fabrication.

Coaxial monitoring of the Direct Energy Deposition (DED) machines enables a real-time material deposition study. Coaxial-images contain substantial melt-pool information and incorporate situational information including the sparks' intensity, numbers, etc. Recent studies have shown that melt-pool observations correlate directly with machine parameters and artifact properties.

Continuous Comprehensive Monitoring of Melt Pool Morphology Under Realistic Printing Scenarios with Laser Powder Bed Fusion.

In laser powder bed fusion (LPBF) additive manufacturing, the melt pool (MP) characteristics are key indicators for process and part defects. For example, the laser scan location on the build plate can slightly change the MP size and shape due to the f-θ optics of the printer. The laser scan parameters can cause variations in MP signatures that may indicate lack-of-fusion and keyhole regimes.

Early detection of capping risk in pharmaceutical compacts.

Capping is a common mechanical defect in tablet manufacturing, exhibited during or after the compression process. Predicting tablet capping in terms of process variables (e.g.

Correlation of solid dosage porosity and tensile strength with acoustically extracted mechanical properties.

Currently, the compressed tablet and its oral administration is the most popular drug delivery modality in medicine. The accurate porosity and tensile strength characterization of a tablet design is vital for predicting its performance such as disintegration, dissolution, and drug-release efficiency upon administration as well as ensuring its mechanical integrity. In current work, a non-destructive contact ultrasonic approach and an associated testing procedure are presented and employed to quantify and relate the acoustically extracted mechanical properties of pharmaceutical compacts to direct porosity and tensile strength measurements.

Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets.

The mechanical properties of a solid dosage, defined by its granular micro-structure and geometry, play a key role in its dissolution profile and performance. An ultrasonic method for extracting the viscoelastic material properties and granular structure of drug tablet compacts is introduced and its utility is demonstrated for tablet compacts made of microcrystalline cellulose (MCC), lactose monohydrate, and sodium starch glycolate as well as magnesium stearate as lubricant. The approach is based on the effect of viscoelasticity and internal micro-structures on the frequency-dependent attenuation of an ultrasonic wave propagating in a granular medium.