Protein misfolding is a biological process that leads to protein aggregation. Anomalous misfolding and aggregation of human superoxide dismutase (hSOD1) into amyloid aggregates is a characteristic feature of amyotrophic lateral sclerosis (ALS), a neurodegenerative illness. Thus, focusing on the L38R mutant may be a wise decision to comprehend the SOD1 disease process in ALS.
View Article and Find Full Text PDFIn this study, we scrutinized the degradation process of phoxim in the presence of Ag+ ions, maintaining a 1:1 molar ratio under diverse temperature conditions. Phoxim was chosen as the model compound to devise experimental methodologies that would shed light on the kinetic and degradation pathways within a time span of 0 to 184 min across varying temperatures. The Arrhenius equation was harnessed to ascertain the activation energies linked with the degradation of phoxim.
View Article and Find Full Text PDFThe presence of antibiotics in water sources is a significant concern due to their potential environmental impact and the risks to human health. In the present research, hierarchically mesoporous UiO-66 (HP-UiO-66) with a high surface area (1011 m/g) and large pore volume was synthesized using the reflux method on the liter scale. The successful synthesis was confirmed by FT-IR, XRD, FESEM/EDS, N-adsorption/desorption, and zeta potential techniques.
View Article and Find Full Text PDFThis study investigates Ni phytoremediation and accumulation potential in the presence of salicylic acid (SA) (0, 50 and 200 μM) and jasmonic acid (JA) (0, 5 and 10 μM) in two populations of Alyssum inflatum under various nickel (Ni) doses (0, 100 and 400 μM). By measuring Ni levels in the shoots and roots, values of bioaccumulation coefficient (BAC), biological concentration factor (BCF) and translocation factor (TF) were calculated to quantify Ni accumulation and translocation between plant organs. Additionally, the amounts of histidine (His), citric acid (CA) and malic acid (MA) were explored.
View Article and Find Full Text PDFTetracycline (TC), as a widely used antibiotic, is very useful in treating bacterial infections. However, its residues in animal foodstuffs can enter the human body through the food cycle and causes severe and chronic diseases. On the other hand, due to its weak non-biodegradability, it is considered a threat to the environment.
View Article and Find Full Text PDFMetallothioneins are a group of cysteine-rich proteins that play an important role in the homeostasis and detoxification of heavy metals. The objective of this research was to explore the significance of metallothionein in Trichoderma harzianum tolerance to zinc. At the inhibitory concentration of 1000 ppm, the fungus adsorbed 16.
View Article and Find Full Text PDFWheat plays a crucial role in global food security, serving as a vital food crop that feeds billions of people worldwide. Currently, Russia and Ukraine are responsible for exporting approximately 25% of the world's wheat, making any issues in these regions a cause for concern regarding global wheat supply. The problems faced in these areas have led to a surge in wheat prices worldwide.
View Article and Find Full Text PDFGlobal food security requires food production to be increased in the future decades. Agro-Ecological Zones (AEZ) methodology is a successful approach used in land evaluation studies to support sustainable agricultural development. This approach can facilitate finding suitable areas for wheat production on a global scale.
View Article and Find Full Text PDFAtropine (AT) is an anticholinergic drug. AT is abundantly in Datura plant seeds. Fe O @Zn/Mg MOF (Fe O @MOF) composite was synthesized.
View Article and Find Full Text PDFThe interaction between genotypes and environments plays an important role in selecting superior genotypes for target locations. The main objectives of the present study were to analyze the effect of the genotype-by-environment interaction (GEI) and identify superior, newly developed, and promising barley genotypes for cold regions in Iran. For these purposes, a set of genotypes obtained from breeding programs for cold climates in Iran, along with two reference genotypes, were investigated at eight research stations (Tabriz, Ardabil, Arak, Miandoab, Mashhad, Jolge Rokh, Karaj, and Hamadan) during two consecutive growing seasons (2019-2020 and 2020-2021).
View Article and Find Full Text PDFOriganum vulgare L., a medicinal and aromatic herb, has been used for hundreds of years. This plant contains valuable chemical compounds that can be used as medicine for treatment.
View Article and Find Full Text PDFAtropine is a tropane alkaloid found in abundance in Datura plant. We used two liquid-liquid extraction methods and magnet solid-phase extraction to compare the amount of atropine in these two types of plants (Datura innoxia and Datura stramonium). The surface magnetic nanoparticle Fe3O4 correction with an amine and dextrin, and finally, magnetic solid-phase extraction Fe3O4@SiO2-NH2-dextrin (MNPs-dextrin), was prepared.
View Article and Find Full Text PDFIn this article; the bimetal metal-organic framework Zn/Mg (Zn/Mg MOF) is synthesized. Then Zn/Mg MOF bimetal was combined with FeO and FeO@SiO, and composites of FeO@ SiO/MOF/Dextrin, FeO@SiO/MOF, FeO@MOF/Dextrin and FeO@MOF made. The peroxidase-like activity of these compounds was investigated and compared by calorimetric Resazurin (Rz) and O-phenylenediamine (OPD); (Rz-HO, OPD-HO) and fluorimetric Rz and terephtalic acid (TA); (Rz-HO, TA-HO).
View Article and Find Full Text PDFThe development of efficient materials and methods for the elimination of heavy metals contamination from water bodies is increasingly demanded as these toxic cations can acute diseases to humans or make serious threat to the environment. The aim of this research is to evaluate the effectiveness of the organosilane coupling agent for the modification of hydrous manganese oxide and the application of the functionalized nanoadsorbent for the removal of nickel and copper ions from synthetic wastewater samples. The synthesized thiol-functionalized hydrous manganese oxide was characterized in terms of their morphology, surface area, functional groups, surface elemental compositions, and the structural properties.
View Article and Find Full Text PDFThe development of efficient strategies for the removal of heavy metal ions from aqueous solutions is rapidly demanded as these contaminants are very toxic and carcinogenic and show detrimental effects on the living creatures. The main focus of the current study is on the preparation and assessment of electrospun adsorptive nanofiber membranes for the removal of toxic Ni(II) and Cu(II) from wastewater in the ultrafiltration process. Hydrothermally synthesized titanate nanotubes (TNT) was modified with thiol functional groups and then directly incorporated to the polyvinyl chloride nanofiber matrices via electrospinning process to fabricate an adsorptive membrane.
View Article and Find Full Text PDFIn this work, Mn-doped ZnS quantum dots capped by L-cysteine (Mn@ZnS/L-cyst) and polyethylene glycol (Mn@ZnS/PEG) and also Mn-doped ZnS on zeolite NaY (Mn@ZnS/Y) were synthesized. These compounds were characterized by Fourier transform infrared (FT-IR), X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), field emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy (EDS), transmission electron microscopy (TEM), and ultraviolet-visible and fluorescence spectroscopy. Then, the photodegradation ability of these three photocatalysts was investigated for degradation of 4',5'-dibromofluorescein dye under ultraviolet irradiation.
View Article and Find Full Text PDFIn this work, a novel and highly fluorescent (FL) metal-organic framework (MOF)-based host-guest hybrid system was developed through encapsulation of polyethylene glycol (PEG)-capped ZnS quantum dots (QDs) into zeolitic imidazolate framework (ZIF)-67 at ambient temperature. This new composite material was characterized by FT-IR, XRD, TEM, UV-Vis absorption and FL spectroscopy, and then exploited as fluorescence sensor for highly sensitive and selective detection of Cu (II) ions in water samples. The as-prepared PEG-ZnS QDs@ZIF-67 nanohybrids took advantages of both accumulation effect in ZIF-67 and FL sensitivity and selectivity in ZnS QDs toward analyte-Cu.
View Article and Find Full Text PDFTo achieve a low methoxy-pectin nanocomposite film with maximum resistance to water and acceptable mechanical properties, the interactions of different glycerol concentrations and Ca ions in both steps of crosslinking on the swelling degree (SD) and mechanical properties of prepared films were investigated using response surface methodology (RSM). Accordingly, quadratic second-order models were fitted to the SD and tensile strength responses; while the cubic model demonstrated a good relation between independent variables and elongation at break respectively. As a compromise between water resistance and mechanical properties of the prepared films, the use of 0.
View Article and Find Full Text PDFNanoparticles of cadmium selenide (CdSe) doped with europium, were synthesized as stabilizing agents using thioglycolic acid ligand. This method is based on the enhancing effect of CdSe quantum dots (QDs) doped with europium on chemiluminescence (CL) emission. This emission was generated by mixing CdSe QDs with manganese (II), iron (II) and chrome (II) sulfates as catalysts in the presence of hydrogen peroxide (H O ).
View Article and Find Full Text PDFIn this study, high-throughput sequencing (RNA-Seq) was utilized to evaluate differential expression of transcripts and their related genes involved in response to terminal drought in root tissues of bread wheat landrace (L-82) and drought-sensitive genotype (Marvdasht). Subsets of 460 differentially expressed genes (DEGs) in drought-tolerant genotype and 236 in drought-sensitive genotype were distinguished and functionally annotated with 105 gene ontology (GO) terms and 77 metabolic pathways. Transcriptome profiling of drought-resistant genotype "L-82" showed up-regulation of genes mostly involved in Oxidation-reduction process, secondary metabolite biosynthesis, abiotic stress response, transferase activity and heat shock proteins.
View Article and Find Full Text PDFMonitoring and assessing toxic materials which are being released into the environment along with wastewater is a growing concern in many industries. The current research describes a highly sensitive and rapid method for the detection of toxic concentrations of heavy metals in aquatic environments. Water samples were collected from southern coasts of the Caspian Sea followed by screening of luminescent bacteria.
View Article and Find Full Text PDFMyiasis is caused by the larvae of flies infesting animal or human tissues and organs. This report aims to present a case of pharyngeal myiasis caused by the larvae of (Diptera: Oestridae). A 55-yr old drug addict living in the Shahindeje village of Western Azerbaijan Province, northwestern Iran was referred to the Emam Reza Hospital in Tabriz, having a medical history of Chronic Obstructive Pulmonary Disease (COPD) and hospitalized due to respiratory distress, 20 days ago.
View Article and Find Full Text PDFObjective: We aimed to assess the effects of obesity-related follicular fluid (FF) fatty acids (FAs) on the number and quality of oocytes, good embryo quality rate, and pregnancy rate.
Materials And Methods: This prospective cohort study was conducted on 105 infertile women under the age of 38, who underwent intracytoplasmic sperm injection (ICSI) from March 2015 to October 2015. They were grouped into three body mass index (BMI) categories.
Background: Our objective was to determine the effect of fatty acids (FAs) in serum and follicular fluid (FF) on fertilization and intracytoplasmic sperm injection (ICSI) outcomes.
Methods: One hundred five women aged 18-38 years undergoing ICSI were recruited in this prospective cohort study. oocyte and emberyo quality was morphologically assessed.
In this study, for the first time, the edible pectin film was reinforced by crystalline nanocelullose (CNC). The incorporation of three levels of CNC (2, 5 and 7% w/w) on mechanical, thermal and water vapor barrier properties of pectin-based biodegradable film were investigated using solution casting evaporation method for film preparation. The optimum result was obtained through the nanocomposite film with 5% CNC in terms of mechanical and water vapor properties as the tensile strength increased up to 84% and water vapor permeability decreased by 40%.
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