Antioxidant and anti-inflammatory activity of Mart. (Açaí) seed bioproducts.

Mart. is a tropical palm tree native to the Amazon region. Its fruit, commonly known as açaí, has gained widespread recognition for its therapeutic potential, driving the expansion of pharmacological studies to validate its traditional uses.

Development and validation of a face database for the recognition of facial expressions of basic emotions in the Brazilian population.

Background: The recognition of facial expressions of emotions is an essential skill for social functioning, as it enables recognizing the possible intentions of others.

Main Body: Cultural context is an important aspect to consider in this skill, as it tends to modulate the recognition of facial expressions.

Objective: To develop and validate a set of facial expressions of basic emotions of Brazilian individuals considering the population distribution of the country according to age group, sex, and race.

Muscle hypertrophy response across four muscles involved in the bench press exercise: Randomized 10 weeks training intervention.

Background And Purpose: Resistance training exercise provides increases in muscle size and is used by coaches and health care professional as a tool to improve functional performance. The aim of the present study was to investigate the effect of 10 weeks of resistance training program performed on the bench press (BP) exercise on the hypertrophic responses of four different muscles (pectoralis major, anterior and medial deltoid, brachii, and pectoralis minor) involved in the task compared to controls.

Methods: Twenty-four healthy males were recruited, and thirteen performed a resistance training intervention while eleven were control.

Data-Driven Cutoff Selection for the Patient Health Questionnaire-9 Depression Screening Tool.

Importance: Test accuracy studies often use small datasets to simultaneously select an optimal cutoff score that maximizes test accuracy and generate accuracy estimates.

Objective: To evaluate the degree to which using data-driven methods to simultaneously select an optimal Patient Health Questionnaire-9 (PHQ-9) cutoff score and estimate accuracy yields (1) optimal cutoff scores that differ from the population-level optimal cutoff score and (2) biased accuracy estimates.

Design, Setting, And Participants: This study used cross-sectional data from an existing individual participant data meta-analysis (IPDMA) database on PHQ-9 screening accuracy to represent a hypothetical population.

Alternative feedstocks for sustainable aviation fuels: Assessment of sugarcane-derived microbial oil.

Pioneer facilities for Sustainable Aviation Fuels (SAF) convert fats, oils, and grease into hydrocarbons using the Hydroprocessed Esters and Fatty Acids (HEFA) technology. However, limited feedstock availability and sustainability concerns may restrict broader adoption. Biotechnology offers an alternative by enabling microbial oil production from sugars, expanding the feedstock portfolio with more productive biomass sources or waste materials.

Segmental histomorphometry of the porcine ureter for use as a vascular xenograft.

Purpose: To histologically quantify the different tissues that make up the porcine ureter, (epithelial, connective, and muscular tissue) in the three segments labelled: cranial, middle and caudal, in order to identify the segment most compatible for use as a vascular graft.

Methods: Fifteen porcine ureters were collected, divided into the three segments, and the samples were stained with hematoxylin and eosin, picrosirius red and Weigert's resorcin-fuchsin. The immunohistochemistry technique was applied for alpha-smooth muscle actin.

Establishment of a Reference Material in Quality Control for Use in Infectivity and Identity Assays of Recombinant COVID-19 Vaccine, in Accordance with International Standards Organization Guidance.

The COVID-19 pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), began in 2019. One of the strategies for pandemic control was mass vaccination. In Brazil, the recombinant COVID-19 vaccine (RCV) was produced on a large scale and offered at no charge to the population.

Telemedicine Rounding Support for Public Health System Pediatric Intensive Care Units in Brazil can Improve Outcomes.

There are discrepancies in resources and expertise available between pediatric intensive care units (PICUs) in Brazil that likely significantly impact the clinical outcomes of patients. The goal of this study was to evaluate the impact of telemedicine rounding support in two public PICUs located in the North and Northeast regions of Brazil. Our intervention involves telehealth rounds connecting two "level II" PICUs with specialist doctors from a hospital of recognized excellence.

Supplying the ethanol demand for 2030 in Brazil as a land-based climate change mitigation alternative: Implications on greenhouse gases emissions.

Transitioning from a fossil-based to a bio-based economy is crucial to climate action and achieving neutrality in greenhouse gas (GHG) emissions. Biofuel production is an essential land-based GHG mitigation alternative. However, it raises concerns about biodiversity conservation, competition with food production, and net GHG emissions associated with direct land-use change (dLUC).

COVID-19 Frequency in Hospitalized Psychiatric Patients: A Systematic Review.

Objective: The COVID-19 pandemic affected individuals in different contexts (e.g. long-term care facilities, schools, communities), including psychiatric hospitals.

Use of rainbow trout skin treated with glutaraldehyde as a mesh for abdominal hernioplasty in rats.

Purpose: To test the use of rainbow trout skin as a surgical mesh in abdominal hernioplasties in rats.

Methods: The experiment involved 20 Wistar rats receiving implants of trout skin processed for disinfection in 0.5% glutaraldehyde and preserved in 100% glycerin.

Carbon savings from sugarcane straw-derived bioenergy: Insights from a life cycle perspective including soil carbon changes.

Sugarcane straw removal for bioenergy production will increase substantially in the next years, but this may deplete soil organic carbon (SOC) and exacerbate greenhouse gas (GHG) emissions. These aspects are not consistently approached in bioenergy life cycle assessment (LCA). Using SOC modeling and LCA approach, this study addressed the life cycle GHG balance from sugarcane agroindustry in different scenarios of straw removal, considering the potential SOC changes associated with straw management in sugarcane-cultivated soils in Brazil.

Understanding the Enzyme ()-Norcoclaurine Synthase Promiscuity to Aldehydes and Ketones.

The ()-norcoclaurine synthase from (NCS) stereoselectively catalyzes the Pictet-Spengler reaction between dopamine and 4-hydroxyphenylacetaldehyde to give ()-norcoclaurine. NCS can catalyze the Pictet-Spengler reaction with various aldehydes and ketones, leading to diverse tetrahydroisoquinolines. This substrate promiscuity positions NCS as a highly promising enzyme for synthesizing fine chemicals.

Molecular detection of Bartonella spp. in bat-associated macronyssid mites (Acari: Macronyssidae) from Southern and Southeastern Brazil.

Despite the worldwide occurrence and high genetic diversity of Bartonella spp. in bats, few studies investigate their occurrence in bat-associated mites. To date, 26 species of Macronyssidae mite species have been reported from Brazil, and 15 of which were found parasitizing bats.

Effects of empathy training on psychological concerns and empathy in caregivers of older people: A randomized, double-blind, crossover, clinical trial with follow-up.

Objectives: To investigate the effects of empathy training on psychological concerns and empathy in caregivers of older people.

Methods: A randomized, double-blind, crossover, clinical trial with follow-up was conducted online. Thirty paid and unpaid caregivers of older people from different regions of Brazil participated in an empathy training program.

Eutrichophilus cordiceps Mjöberg, 1910 (Ischnocera: Trichodectidae) in Spiny Tree Porcupines (Coendou villosus): New locality records and the first molecular evidence of association with Bartonella sp.

The chewing louse genus Eutrichophilus Mjöberg has 19 species only associated with porcupines (Rodentia: Erethizontidae). Of these species, E. cercolabes, E.

Does rest interval between unilateral exercise protocols influences on contralateral neuromuscular responses in untrained individuals?

Introduction: Effects on strength performance and muscle activation in the contralateral limb have been observed after training with the ipsilateral limb (IL). Cross fatigue effects in the contralateral limb (CL) can occur at intervals of up to 48 h after a training session performed with the ipsilateral limb. The objective of this study was to verify the effect of a training session in the ipsilateral limb, on the strength and activation of the muscles in the contralateral limb also submitted to the training protocol.

Factors associated with happiness among community-dwelling older adults: a systematic review.

Objectives: To identify factors associated with self-reported happiness among community-dwelling older adults.

Methods: A systematic review of the literature was conducted. Searches were conducted in the PsycInfo, Web of Science, Scopus and Pubmed databases for relevant articles published in English, Spanish or Portuguese using the following search strategy and Boolean operators: (happiness*) AND (elder* OR (old adult*)).

Boolean model of the gene regulatory network of CCBH4851.

Introduction: infections are one of the leading causes of death in immunocompromised patients with cystic fibrosis, diabetes, and lung diseases such as pneumonia and bronchiectasis. Furthermore, is one of the main multidrug-resistant bacteria responsible for nosocomial infections worldwide, including the multidrug-resistant CCBH4851 strain isolated in Brazil.

Methods: One way to analyze their dynamic cellular behavior is through computational modeling of the gene regulatory network, which represents interactions between regulatory genes and their targets.

Development and validation of a brief digital cognitive test based on the paradigm of stimulus equivalence in a sample of older adults.

Unlabelled: With the technological advancement and democratization of electronic devices, computerized cognitive tests have been increasingly used in the clinical context to evaluate cognitive performance in individuals.

Objective: This study aimed to propose a brief digital cognitive test based on the paradigm of stimulus equivalence and assess its convergent validity by comparing it with traditionally applied tests.

Methods: The study was carried out with a non-probabilistic sample of 50 older adults selected from a public call through the communication media, health units, and day centers of a city in the countryside of São Paulo.

Histochemical analysis, smooth muscle immunolocalization and volumetric density of the elastic system fibres of the ostrich (Struthio camelus) phallus.

There are few scientific reports on the histology of the phallus of ratite birds. The aim of this study was to conduct a histochemical analysis to determine the distribution of smooth muscle cells and the volumetric density (Vv) of the fibres of the elastic system in the ostrich phallus. Adult ostriches, 14 months old, were used.

Avocado Oil () Reduces Epithelial Proliferation on Benign Prostatic Hyperplasia.

Objective: The aim of this study is to evaluate the effect of avocado oil on the histoarchitecture of the prostate of normal rats and on rats with induced benign prostatic hyperplasia using computerized histomorphometry and immunohistochemistry.

Methods: Twenty-eight Wistar rats were divided into four groups: the control group (CG), the avocado oil group (AOG) fed with avocado oil-based diet, the induced group (IG), and the avocado oil testosterone-induced group (AOIG). Prostate hyperplasia was induced by subcutaneous implantation of silicone pellets, filled with testosterone, to promote androgen stimulation.

Effects of the Acute and Chronic Administration of Cannabidiol on Cognition in Humans and Animals: A Systematic Review.

The effects of cannabidiol (CBD) on cognition has been investigated in recent years to determine the therapeutic potential of this cannabinoid for a broad gamut of medical conditions, including neuropsychiatric disorders. The aim of the present study was to perform a systematic review of studies that analyzed the effects of the acute and chronic administration of CBD on cognition in humans and animals both to assess the cognitive safety of CBD and to determine a beneficial potential of CBD on cognition. The PubMed, Web of Science, PsycINFO, and Scopus databases were searched in December of 2022 for relevant articles using the following combinations of keywords: ("cannabidiol" OR "CBD") AND ("cognition" OR "processing cognitive" OR "memory" OR "language" OR "attention" OR "executive function" OR "social cognition" OR "perceptual motor ability" OR "processing speed").