Publications by authors named "Chae Dong Yim"
Article Synopsis
- * Researchers analyzed bacterial samples from patients over 17 years using genetic methods to determine the strains' diversity and virulence.
- * The findings revealed that the strains from refractory cases were mostly of sequence type 235 (ST235), which is highly virulent and resistant to antibiotics, suggesting the need for better management and patient education.
Article Synopsis
- - The study explored the role of sirtuin 4 (SIRT4) in papillary thyroid carcinoma (PTC), using data from The Cancer Genome Atlas (TCGA) and analyzing SIRT4 expression in 205 PTC samples to see its correlation with clinical outcomes.
- - Results showed that lower SIRT4 levels in thyroid cancer are linked to worse survival rates, with SIRT4 overexpression leading to decreased cell survival and invasion in thyroid cancer cell lines, as well as increased apoptosis.
- - The findings suggest SIRT4 acts as a tumor suppressor in PTC, regulating processes like epithelial-mesenchymal transition, and call for further investigation into the underlying molecular mechanisms.
Background: Gastric cancer, one of the leading causes of cancer-related death, is strongly associated with infection, although other risk factors have been identified. The sirtuin (Sirt) family is involved in the tumorigenesis of gastric cancer, and sirtuins can have pro- or anti-tumorigenic effects.
Methods: After determining the overall survival rate of gastric cancer patients with or without Sirt6 expression, the effect of Sirt6 upregulation was also tested using a xenograft mouse model.
Purpose This study aimed to report an unusual case of benign paroxysmal positional vertigo (BPPV), who showed prolonged positional downbeat nystagmus without latency and was diagnosed with cupulolithiasis of the anterior canal (AC). We compared this case with one of typical AC-BPPV, and possible mechanisms underlying the atypical characteristics were discussed. Method Two patients diagnosed with AC-BPPV were reported.
View Article and Find Full Text PDFObjectives: We investigated the incidence and characteristics of pseudo-spontaneous nystagmus (PSN) in benign paroxysmal positional vertigo involving the lateral semicircular canal (LC-BPPV) and evaluated the correlation between PSN and the bow and lean test.
Methods: We examined nystagmus in the sitting position using video-oculography goggles in 131 LC-BPPV patients. The positioning test and bow and lean test were also performed.
IgG4-related disease presenting as otogenic skull base osteomyelitis.
Auris Nasus Larynx
February 2021
IgG4-related disease (IgG4-RD) is an emerging clinical disease entity characterized by tumefactive lesions at multiple sites with a dense lymphoplasmacytic infiltrate rich in IgG4+ plasma cells. Although almost any organ can be affected, IgG4-RD is most likely to involve the submandibular, lacrimal, or parotid glands in the head and neck region. However, skull base involvement presenting as otogenic skull base osteomyelitis (SBO) is rare.
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