Acute masticatory muscle compartmental syndrome in a dog.

CASE DESCRIPTION A5.5-year-old sexually intact male Bull Terrier was referred for evaluation because of sudden facial swelling and an inability to close its mouth. CLINICAL FINDINGS Physical examination revealed bilaterally elevated nictitating membranes, an inability to adduct the mandible without assistance, and severe, diffuse, firm masticatory muscle swelling.

Assessment of antiepileptic drugs as substrates for canine P-glycoprotein.

Objective: To determine whether antiepileptic drugs (AEDs) are substrates for canine P-glycoprotein (P-gp). Sample Population-OS2.4/Doxo cells (canine osteosarcoma cells induced via exposure to doxorubicin to highly express P-gp).

Cerebrospinal fluid analysis and magnetic resonance imaging in the diagnosis of neurologic disease in dogs: a retrospective study.

Background: Diagnosis of central nervous system (CNS) abnormalities in dogs can be challenging antemortem. Historically, cerebrospinal fluid (CSF) analysis has been used for routine diagnostic evaluation of animals with suspected neurologic disease; however, with increasing availability of magnetic resonance (MR) imaging, the need for concurrent CSF analysis may be questioned.

Objective: The purpose of this study was to retrospectively assess and compare the diagnostic information contributed from MR imaging and CSF analysis in a population of dogs presenting with neurologic disease.

Fecal incontinence and spinal cord abnormalities in seven dogs.

Seven dogs with fecal incontinence and abnormal gaits were evaluated. Fecal incontinence was characterized as defecation of normal stools without posturing. Duration of clinical signs prior to evaluation ranged from 5 months to 3 years.