Iron Deficiency in Attention-Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Internalizing and Externalizing Disorders, and Movement Disorders.

This article reviews the role of iron in brain development and function, with a focus on the association between iron deficiency (ID) and neuropsychiatric conditions. First, we describe how ID is defined and diagnosed. Second, the role of iron in brain development and function is summarized.

Iron deficiency in pediatric patients in long-term risperidone treatment.

Objective: Atypical antipsychotics, increasingly used in children and adolescents, modulate brain dopamine. Iron plays a critical role in dopaminergic signaling. Therefore, we explored whether body iron status is related to psychiatric symptom severity, treatment response, and tolerability following extended antipsychotic therapy.

Correlates of weight gain during long-term risperidone treatment in children and adolescents.

Background: Most clinical trials of antipsychotics in children are brief, failing to address their long-term safety, particularly when taken concurrently with other psychotropics. This hypothesis-generating analysis evaluates potential correlates of weight gain in children receiving extended risperidone treatment.

Methods: Medically healthy 7-17 year-old patients treated with risperidone for six months or more were enrolled.

Predictors of risperidone and 9-hydroxyrisperidone serum concentration in children and adolescents.

Introduction: Little is known about risperidone metabolism in a clinical sample, where polypharmacy is common. Such knowledge is important since several of its side effects are dose dependent.

Methods: Medically healthy patients aged 7 to 17 years old treated with risperidone for at least 6 months were enrolled.