Publications by authors named "Chadha N"

Ammonia, a major stress-inducing factor in aquaculture, contributes a significant challenge in maintaining sustainable fish production. Addressing this issue requires environmentally and economically sustainable solutions. This study explores the use of readily available and environmentally friendly porous lignocellulosic luffa sponge as a biostimulator, with a combination of three medicinal and aromatic plants(MAPs) viz.

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Background: Qualitative experience data can inform health care providers how to best support families during pediatric postoperative recovery. Patient experience data can also provide actionable information to guide health care quality improvement; positive feedback can confirm the efficacy of current practices and systems, while negative comments can identify areas for improvement.

Objective: This study aimed to understand families' perspectives regarding their children's surgical recovery using qualitative patient experience data (free-text comments) from a prospective cohort study conducted within a larger study developing a postoperative-outcome risk stratification model.

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Background: Recurrent infections of the nose, sinuses and ears are common problems for people with primary ciliary dyskinesia. While pulmonary exacerbations in primary ciliary dyskinesia are defined, there is no definition for ear-nose-throat exacerbations, a potential outcome for research and clinical trials.

Methods: We set up an expert panel of 24 ear-nose-throat specialists, respiratory physicians, other healthcare professionals and patients to develop consensus definitions of sinonasal and otological exacerbations in children and adults with primary ciliary dyskinesia for research settings.

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Effects of environmentally relevant ultraviolet B (UVB) light on the embryonic development of a high-altitude dwelling endangered fish, Tor putitora (golden mahseer), were investigated for the first time. For that, three sets of embryos (in triplicates) were exposed to various ambient UVB light doses (1, 2 and 3 W/m, corresponding to 3.6, 7.

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Article Synopsis
  • Chronic respiratory disease (CRD) rates are increasing in Asia, and pulmonary rehabilitation (PR) has proven effective in treating this condition; however, cultural and environmental factors may affect how PR programs are implemented in Asia.
  • A comprehensive review analyzed 137 studies across various databases to assess the characteristics of CRD rehabilitation programs in Asia compared to the 2023 American Thoracic Society (ATS) guidelines, revealing significant variation in approaches.
  • While most programs included aerobic exercises, only about 22% adhered closely to the ATS guidelines, highlighting a need for a balance between local adaptations of PR and maintaining the core principles of effective rehabilitation programs.
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Cypermethrin is a pyrethroid insecticide used in aquaculture farms against ectoparasites. The conventional pesticide formulations are now being found to be greatly ineffective at low dosages, and their indiscriminate usage may cause undesired effects in ecosystems. So, the current study was designed to develop a nanoformulation of cypermethrin that would have many advantages over conventional pesticide formulations, and the toxic effects of this formulation were then tested on the carp Labeo rohita fingerlings.

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Article Synopsis
  • First branchial cleft anomalies are rare issues in the head and neck area that some kids are born with, and there's not much info on how to classify or treat them properly.
  • * Expert doctors worked together to come up with better ways to identify and manage these anomalies using a method called the Delphi method.
  • * They created a new classification system and treatment guidelines to help doctors give better care to kids with these conditions.
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Identifying hepatic fibrosis is paramount in managing patients with chronic liver disease. The etiology of liver disease can be owing to many factors, including chronic viral hepatitis, steatotic liver diseases such as alcohol-associated liver disease or metabolic dysfunction-associated steatotic liver disease, autoimmune hepatitis, and cholestatic liver diseases. Currently, invasive liver biopsy with histopathologic evaluation is the gold standard; however, noninvasive tests are becoming more prevalent, especially because they do not carry the risks of invasive procedures such as biopsy.

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Article Synopsis
  • Pediatric acute otitis media (AOM) is common in children, leading to concerns about overdiagnosis and overtreatment, prompting the need for specific quality indicators (QIs).
  • An expert panel, utilizing the RAND/UCLA methodology, evaluated candidate indicators and ultimately agreed on 8 QIs related to antimicrobial management, referrals, and counseling for tympanostomy tubes.
  • These QIs aim to address the inconsistent care in AOM diagnosis and management, enhancing adherence to guidelines and improving patient outcomes.
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Background And Objectives: Examination anxiety is a common occurrence, and is potentially detrimental to student attainment. In recent theorizing, it has been suggested that cognitive appraisals, as put forth in cognitive appraisal theory, and irrational beliefs, as put forth in rational emotive behavior therapy, may interact to predict affectivity. The current research examines the antecedents and associates of examination affect and academic self-concept in undergraduate students.

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Background: Pandemic public health measures, such as masks and social distancing, present unique challenges for people who are hard-of-hearing. This study sought to understand how adolescents with varying levels of hearing loss would describe their experiences communicating in a classroom environment during a pandemic and its associated public health measures.

Methods: Qualitative study utilizing one-on-one semi-structured interviews conducted from July 2021 to April 2022.

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Objective: Three-dimensional (3D) endoscopy has been developed to provide depth perception to allow for improved visualisation during otolaryngology surgery. We conducted a systematic review to determine the surgical safety and efficacy of 3D endoscopy in comparison to two-dimensional (2D) endoscopy in performing otolaryngology procedures, and the role of 3D endoscopy as a training tool for novice otolaryngology surgeons.

Methods: Primary studies were identified through MEDLINE, Embase and Web of Science databases, which were searched for articles published through June 2022 that compared the outcomes of 2D and 3D endoscopy in otolaryngology surgical procedures or otolaryngology-relevant simulations.

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Purpose: Artificial intelligence (AI) is already impacting the practice of medicine and it is therefore important for future healthcare professionals and medical educators to gain experience with the benefits, limitations, and applications of this technology. The purpose of this project was to develop, implement, and evaluate a faculty development workshop on generative AI using ChatGPT, to familiarise participants with AI.

Materials And Methods: A brief workshop introducing faculty to generative AI and its applications in medical education was developed for preclinical clinical skills preceptors at our institution.

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Objective: To determine the carbon savings potential of incorporating virtual care into surgical care pathways for pediatric patients with obstructive sleep apnea or otitis media with effusion.

Methods: Pediatric patients with obstructive sleep apnea or otitis media with effusion were not enrolled, instead, a modeling cohort study design was used. This study utilized the British Columbia healthcare system and geography to model emissions.

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Emotion regulation through cognitive reappraisal is well-studied, but less so are the predispositional and superordinate beliefs that influence reappraisal. Recently, researchers developed the cognitive mediation beliefs questionnaire (CMBQ), which measures two emotion beliefs, namely stimulus-response (S-R) generation beliefs and cognitive mediation (C-M) change beliefs. In working populations S-R generation beliefs are inversely related to cognitive reappraisal tendencies and positive mental health, and positively related to emotion reactivity.

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Objective: In rare situations, neonates may present with respiratory distress and neck swelling from a piriform fossa sinus tract (PFST) lesion. Open surgical excision of PFST may be associated with higher complication rates, especially in neonates. Endoscopic treatment has been shown to have high success rates in older children, but neonatal outcomes appear to be less promising.

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Translating high-confidence (hc) autism spectrum disorder (ASD) genes into viable treatment targets remains elusive. We constructed a foundational protein-protein interaction (PPI) network in HEK293T cells involving 100 hcASD risk genes, revealing over 1,800 PPIs (87% novel). Interactors, expressed in the human brain and enriched for ASD but not schizophrenia genetic risk, converged on protein complexes involved in neurogenesis, tubulin biology, transcriptional regulation, and chromatin modification.

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Article Synopsis
  • Insulin-like growth factors (IGFs) are crucial for growth in vertebrates, and the GH-IGF axis can be used to monitor fish growth performance, particularly in butter catfish (Ompok bimaculatus).
  • The study examines the molecular characteristics and expression levels of igf-1 and igf-2 in the liver and muscle of fish under varying stocking densities over a 180-day culture period, revealing that igf-1 expression decreases at higher densities while igf-2 remains stable.
  • The research finds that igf-1 is a better growth regulator related to culture density, with potential implications for improving harvest scheduling and optimizing culture practices in aquaculture.
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Researchers have intimated that cognitions and emotions can change in the lead up to important events. However, previous research has adopted atemporal cross-sectional designs, making it challenging to understand how cognitions and emotions unfold in the lead up to a competition. In the current study, we extended previous research by examining the temporal patterns of cognitive appraisals, irrational beliefs, and challenge and threat evaluations in predicting pre-competitive affective states (hedonic balance and anxiety) in the lead up to an actual competition, among competitive elite Indian golfers (N = 107).

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Purpose: To explore and report on how glaucoma care was impacted by the SARS-CoV-2 pandemic (COVID-19) in New York City (NYC) with a specific emphasis on the role of telemedicine.

Patients And Methods: This was a qualitative, cross-sectional study that engaged glaucoma clinicians in semi-structured interviews to elicit perspectives on telemedicine and patient care experiences during the pandemic. Interview responses were coded and analyzed thematically.

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Purpose: To evaluate medical student perceptions of a novel ophthalmology resource delivered through facilitated workshops in the core clerkship curriculum.

Methods: We created www.2020sim.

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Background: Given limited pre-residency ophthalmology exposure, skill training for PGY-2 ophthalmology residents is essential. However, orientation experiences vary, and skills acquisition is often not measured.

Objective: A novel video-based orientation curriculum was developed and implemented to standardize and effectively teach ophthalmic examination skills to incoming ophthalmology residents.

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