Relationship between breastfeeding and hepatic steatosis in women with previous gestational diabetes mellitus.

Background: Non-alcoholic fatty liver disease (NAFLD), characterized by excess liver fat, is common in women with a history of gestational diabetes mellitus (GDM). While breastfeeding improves postpartum lipid levels, its impact on NAFLD in these women is not well studied. We aimed to investigate the relationship between the duration and intensity of breastfeeding and the amount of liver fat and prevalence of NAFLD in women with previous GDM at approximately 1 year postpartum.

Lactation duration and development of type 2 diabetes and metabolic syndrome in postpartum women with recent gestational diabetes mellitus.

Background: The World Health Organization and United Nations Children's Fund recommend exclusive breastfeeding (EBF) for the first six months of an infant's life. Although evidence suggests that maintaining breastfeeding has positive impacts on glucose and lipid metabolism in postpartum women with a history of gestational diabetes mellitus (GDM), no study has investigated whether such effects differ between breastfeeding intensities. This study aimed to evaluate the impact of maintaining breastfeeding on prediabetes, type 2 diabetes mellitus (T2DM), and metabolic syndrome (MetS) six months postpartum in women with GDM.

Impact of postpartum weight change on metabolic syndrome and its components among women with recent gestational diabetes mellitus.

Background: While postpartum weight changes may affect the levels of metabolic parameters, the direct effects of weight changes in the postpartum period on changes in the prevalence rates of metabolic syndrome and its components remain unstudied. This study aimed to investigate the effects of postpartum weight changes between 6 weeks and 6 months on changes in the prevalence rates of metabolic syndrome and its components in women who have recently experienced gestational diabetes mellitus.

Methods: This prospective cohort study included 171 postpartum women with recent gestational diabetes mellitus, who underwent serial weight and metabolic risk factor assessments at 6 weeks and 6 months postpartum.

Effect of prenatal counseling on postpartum follow-up and contraceptive use in women with gestational diabetes mellitus: a randomized controlled trial.

Background: Postpartum visit attendance for glucose screening and uptake of effective contraception is crucial after a pregnancy with gestational diabetes mellitus. Although postpartum women with recent gestational diabetes mellitus are generally advised in the early postnatal period to attend postpartum visits, data have shown suboptimal rates of postpartum glucose testing and of highly effective contraceptive use among these women. Compared with the early postnatal period, the antenatal period is when women and healthcare providers have more contact.

Long-term observational study of renal outcome after preeclampsia: Role of soluble fms-like tyrosine kinase-1(sFlt-1)/ placental growth factor (PlGF) and endoglin.

Introduction: Preeclampsia (PE) is an important complication of pregnancy that can lead to chronic kidney disease. Soluble fms-like tyrosine kinase-1 (sFlt-1), placental growth factor (PlGF), the sFlt-1/PlGF ratio and endoglin are biomarkers for the differential diagnosis of PE and other diseases. We aimed to explore the correlation of these biomarkers with long-term renal function, blood pressure and the urine albumin/creatinine ratio (UACR) in PE patients.

Acceptance of COVID-19 vaccination during pregnancy among Thai pregnant women and their spouses: a prospective survey.

Background: Vaccination is one of the most reliable interventions against coronavirus disease 2019 (COVID-19). Although pregnant women's attitudes toward COVID-19 vaccination are well studied, husbands' views toward COVID-19 vaccination for these women have not been surveyed. We aimed to determine the rates and associated factors of accepting attitudes toward COVID-19 vaccination during pregnancy among Thai pregnant women and their spouses and to evaluate the actual rate of vaccination during pregnancy among these women.

Glucose levels during gestational diabetes pregnancy and the risk of developing postpartum diabetes or prediabetes.

Background: Blood glucose levels during pregnancy may reflect the severity of insulin secretory defects and/or insulin resistance during gestational diabetes mellitus (GDM) pregnancy. We hypothesized that suboptimal glycemic control in women with GDM could increase the risk of postpartum type 2 diabetes mellitus (T2DM) or prediabetes. Our objective was to evaluate the impact of plasma glucose levels throughout GDM pregnancy on the risk of postpartum T2DM or prediabetes.

Risk score for predicting primary cesarean delivery in women with gestational diabetes mellitus.

Background: Women with gestational diabetes mellitus (GDM) have a higher risk of cesarean delivery (CD) than glucose-tolerant women. The aim of this study was to develop and validate a risk score for predicting primary CD in women with GDM.

Methods: A risk score for predicting primary CD was developed using significant clinical features of 385 women who had a diagnosis of GDM and delivered at our institution between January 2011 and December 2014.

Characteristics associated with loss to post-partum follow-up among adolescent mothers.

Aim: To identify the rate and associated factors of loss to post-partum follow-up among adolescent mothers.

Methods: A matched case-control study was conducted among Thai adolescents who gave birth between January 2011 and December 2016 and were scheduled for a 6-week post-partum visit. Cases (n = 568) included mothers who did not return for follow-up whereas controls (n = 568) were mothers who attended a post-partum visit.

Maternal characteristics and pregnancy outcomes among illicit drug-using women in an urban setting.

Objective: To identify characteristics and pregnancy outcomes among pregnant illicit drug users living in an urban area, and to describe trends in drug use over an 8-year period.

Materials And Methods: Data on pregnant women living in the Bangkok Metropolitan Region who delivered at our institution during 2008-2015 were studied. Women with drug use (n = 197) and women without drug use (n = 787) were compared in terms of maternal characteristics and pregnancy outcomes.

Inappropriate gestational weight gain among teenage pregnancies: prevalence and pregnancy outcomes.

Objective: To study the prevalence and pregnancy outcomes of inappropriate gestational weight gain (GWG) among teenage pregnant women.

Methods: A retrospective descriptive study was conducted on 2,165 teenage pregnant women who attended our antenatal clinic between January 2007 and August 2015. Adverse pregnancy outcomes, including maternal and neonatal outcomes of women with inappropriate GWG, including underweight and overweight, were studied and compared with those of women with appropriate GWG.

Timing of elective cesarean delivery at term and its impact on maternal and neonatal outcomes among Thai and other Southeast Asian pregnant women.

Aim: The impact of timing of elective cesarean delivery (CD) at term on maternal and neonatal outcomes among Thai and other Southeast Asian pregnancies was investigated. The rate of spontaneous labor before the scheduled CD, as well as maternal characteristics predicting spontaneous labor, was also evaluated.

Methods: Data on maternal and neonatal outcomes of 1221 singleton pregnancies scheduled for either an elective repeat CD or an elective primary CD at 37-40 weeks of gestation were studied.

Comparison of tissue adequacy for histologic examination from Ipas MVA plus and Wallach Endocell in women with abnormal uterine bleeding.

Aim: The aim of this study was to compare endometrial tissue adequacy sampling by Wallach Endocell and manual vacuum aspiration (Ipas MVA plus) in women with abnormal uterine bleeding. Pain and immediate complications from each method were also compared.

Material And Methods: Two hundred and forty women with abnormal uterine bleeding were randomly assigned to two methods of endometrial sampling: MVA (n = 122) and Endocell (n = 118).

Risk score comprising maternal and obstetric factors to identify late preterm infants at risk for neonatal intensive care unit admission.

Aim: The aim of this study was to develop and validate an antepartum risk score based on maternal and obstetric characteristics to predict the requirement for neonatal intensive care unit (NICU) admission among late preterm infants.

Material And Methods: A chart review was performed of 455 singleton late preterm deliveries at our institution between July 2010 and December 2011. Logistic regression analysis was used to develop a risk score, which was derived from β coefficients of the significant variables.

Comparison of gestational diabetes mellitus rates in women with increased and normal white blood cell counts in early pregnancy.

Aim: To compare the rates of gestational diabetes mellitus (GDM) among Thai or other South-East Asian women with increased and normal peripheral white blood cell (WBC) counts in early pregnancy. The risk of GDM in relation to WBC count was also determined.

Methods: We included singleton pregnant women who sought their first antenatal care in our institution between May 2010 and December 2011.

Seasonal variation in the prevalence of preeclampsia.

Objective: To determine whether there is a seasonal impact on the prevalence of preeclampsia in the tropical climate of Bangkok.

Material And Method: Medical records of all singleton pregnant women who delivered in the authors' institution between 2008 and 2009 were reviewed. The meteorological variables during the study period were obtained from database of the Thai Meteorological Department.

Pain control in laparoscopic gynecologic surgery with/without preoperative (preemptive) parecoxib sodium injection: a randomized study.

Objective: To determine the effectiveness of preoperative parecoxib sodium injection for pain relief after laparoscopic gynecologic surgery.

Material And Method: A prospective double-blind, randomized study was conducted in 268 patients who underwent laparoscopic gynecologic surgery at Vajira Hospital between November 1, 2010 and March 31, 2011. The patients were randomly allocated into two groups to receive either single intravenous 40 mg parecoxib (treatment group; n = 133) or normal saline (control group; n = 135) 30 min before surgery.

Role of neutrophil to lymphocyte ratio as a prognostic indicator for epithelial ovarian cancer.

Objective: To determine whether level of preoperative peripheral blood neutrophil to lymphocyte ratio (NLR) was a prognostic indicator for epithelial ovarian cancer (EOC) patient. The present study further aimed to evaluate the impact of the change of preoperative/postoperative NLR on the survival.

Material And Method: Medical records of the patients undergoing an operation for EOC in Vajira Hospital between January 1, 2004 and December 31, 2009 were reviewed.

Risk assessment for preeclampsia in women with gestational diabetes mellitus.

Aim: To develop a clinical model to assess the risk of preeclampsia in women with gestational diabetes mellitus (GDM).

Methods: We studied clinical characteristics of 813 consecutive women who had GDM between January 2003 and February 2008 at our institution. The clinical features which were significantly associated with preeclampsia by multiple logistic regression analysis were integrated into a risk model.

A risk score for selective screening for gestational diabetes mellitus.

Objective: To develop a risk score to predict women who are likely to have an abnormal glucose challenge test (GCT) for gestational diabetes mellitus (GDM) screening.

Study Design: A cohort of 1876 pregnant women who underwent a GCT between March 2005 and December 2005 at our institution were studied. A multivariable analysis was performed to determine the clinical features that were significantly associated with an abnormal GCT.

Prevalence of exclusive breastfeeding at 3, 4 and 6 months in Bangkok Metropolitan Administration Medical College and Vajira Hospital.

Objective: To determine the prevalence of exclusive breastfeeding at 3, 4, and 6 months postpartum in women who delivered at Bangkok Metropolitan Administration Medical College and Vajira Hospital, and to evaluate the potential factors for continuation of exclusive breastfeeding.

Material And Method: A prospective descriptive study was performed in 210 mothers who delivered in the authors' institution between December 1, 2006 and February 28, 2007. All eligible subjects were interviewed before discharge from the hospital.

Use of oral glucose tolerance test in early pregnancy to predict late-onset gestational diabetes mellitus in high-risk women.

Aim: To evaluate if any single plasma glucose level from the four values of the normal 100-g oral glucose tolerance test (OGTT) in early pregnancy (< or =20 weeks of gestation) could predict gestational diabetes mellitus (GDM) diagnosed from a second OGTT in late pregnancy (28-32 weeks).

Methods: Glucose levels of pregnant women at high-risk for GDM, who had had a normal early OGTT, and who underwent the second test in late pregnancy, were studied. Each of the four plasma glucose values of the early OGTT was determined for sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV).

Impact of high maternal hemoglobin at first antenatal visit on pregnancy outcomes: a cohort study.

Aim: To determine whether high maternal hemoglobin (Hb) at first antenatal visit is associated with adverse pregnancy outcomes.

Methods: A retrospective cohort study was conducted in 920 singleton pregnancies who started their antenatal booking in the first trimester (125 g/L) were matched 1:1 with those who had normal Hb values (110-124 g/L) according to age group and parity.