Publications by authors named "Chad A Bechtle"
Article Synopsis
- - The vertebrate lens is a useful model for understanding how cells undergo terminal differentiation, particularly through the role of fibroblast growth factors (FGFs).
- - Research shows that having just one functioning copy of the FGF receptor genes 2 or 3 is enough for normal lens development, while the absence of FGF receptor 1 leads to serious eye issues like cataracts.
- - Comprehensive deletion of all three FGF receptors results in major lens defects, highlighting that while FGF signaling is crucial for lens fiber differentiation, the receptors can compensate for one another in their functions.
