Objective: The aim of this study was to establish the physiologic changes in hemostasis during pregnancy and to find the association between the factor V Leiden mutation and adverse pregnancy outcome.
Methods: We investigated blood samples of 148 pregnant women during each trimester of pregnancy. We measured their serum concentrations of factors I, II, V, VII, VIII, IX, X, XI, XII, D-dimers, prothrombin time, INR, aPTT, activity of protein C and S, antithrombin III and platelet count.
Over the last two to three decades, there has been a 15-25 % increase in many countries in the number of women giving birth to large infant. Fetal macrosomia is associated with an increased risk of complications both for the mother and the newborn. In current obstetrics, the macrosomic fetus represents a frequent clinical challenge.
View Article and Find Full Text PDFActa Medica (Hradec Kralove)
February 2012
Objective: The aim of this prospective study was to find the association between the factor V Leiden mutation and adverse pregnancy outcomes.
Methods: This study is an analysis of a prospective observational study of the frequency of placenta-mediated complications of factor V Leiden mutation carriers. We compared pregnancy outcomes of 11 women with a heterozygous form of the factor V Leiden mutation with 41 women of a control group.
Bratisl Lek Listy
March 2010
Objective: To evaluate clinical care for HIV positive pregnant women who delivered in Slovakia from 1985 till 2008.
Background: National guidelines for the prevention of mother-to-child transmission of HIV have not yet been established.
Method: Retrospective analysis of 14 HIV-infected pregnant women and their infants.
The effect of the addition of zeolite to pig feed ration was studied in the cage rearing system under production conditions. Zeolite was mixed in the COS I and COS II feed mixtures directly in the feed plant, the mixing ratio being 100 kg feed mixture + 5 kg zeolite. The feed mixture was administered in granular form ad libitum.
View Article and Find Full Text PDFZentralbl Gynakol
December 1983
Arch Geschwulstforsch
January 1975