Publications by authors named "Chaamanti S Menon"
Article Synopsis
- The TICH-2 trial found no significant improvements in death and dependency outcomes at 90 days after administering tranexamic acid for intracerebral hemorrhage (ICH), but it suggested that recovery from stroke may take longer than three months.
- The study included 2325 patients, with outcomes assessed at one year using various scales, and showed that tranexamic acid did not lead to better functional results at that time, though it associated with a lower mortality rate.
- Despite the potential for reduced mortality, the conclusion emphasizes caution as these findings come from a secondary analysis of a trial that did not show overall benefits.
Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage.
Cochrane Database Syst Rev
October 2023
Background: Outcome after acute spontaneous (non-traumatic) intracerebral haemorrhage (ICH) is influenced by haematoma volume. ICH expansion occurs in about 20% of people with acute ICH. Early haemostatic therapy might improve outcome by limiting ICH expansion.
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