Early administration of intracoronary verapamil improves myocardial perfusion during percutaneous coronary interventions for acute myocardial infarction.

Background: Intracoronary calcium-channel blockers administered in the event of no reflow during percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI) have been shown to improve myocardial perfusion.

Study Objective: To evaluate the effects of the administration of intracoronary verapamil before the occurrence of no reflow during direct PCI.

Design And Setting: Single-center, nonrandomized, prospective study with a retrospective control group.