[Initial stages of protein assimilation in artificial feeding in an experiment].

The content of pepsinogen in the gastric mucosa and acid phosphatase activity in the gastric chyme are adaptively altered in animals with change from natural to artificial feeding. This change is attended by redistribution of gly-gly-dipeptidase activity along the small intestine. It has been established that fibrinogen and casein are characterized by similar values of the compensation coefficient.

[Proteolysis of blood plasma proteins in the stomach in early ontogeny].

Proteolysis of milk substitutes containing fibrinogen, casecid and bovine serum albumin as protein components was studied. Artificial feeding of newborn rats has shown high casecid and fibrinogen utilization. Casecid and fibrinogen contained in milk substitutes delayed protein evacuation from the stomach, while bovine serum albumin intensified protein evacuation.

[Comparative study of splitting of fibrinogen and bovine serum albumin by digestive proteinases].

Fibrinogen attackability by digestive proteinases rises insignificantly after thermodenaturation and does not change after exposure to the denaturation action of urea. The degree of fibrinogen splitting by digestive proteinases is considerably lower as compared to that of the globular protein such as bovine serum albumin.

[Characteristics of protein digestion in artificial feeding in an experiment].

It has been established that during artificial feeding with milk substitute containing different protein components (casecite, bovine serum albumin, fibrinogen), the proximal-distal gradient of cavitary digestion of proteins is observed, with this gradient being more demonstrable as compared with natural feeding of postnatal animals. It has been shown that during experimental natural feeding, the proximal-distant gradient is observed in the distribution of acid proteinases in the small bowel, whereas during artificial feeding one can see a uniform distribution of acid proteinases in the proximal and distal parts of the small bowel. The activity of acid proteinases in the gastric mucosa of 18-day-old animals kept on natural feeding does not differ from the activity of these proteinases under artificial feeding with a substitute containing casecite as protein component.