Atherosclerosis and cancer: common pathways on the vascular endothelium.

This article reviews experimental and clinical data on atherosclerosis and cancer showing common pathogenic mechanisms. It is suggested that common pathways follow dysfunction of the vascular endothelium. The activation of the haemostatic system and the overexpression of cytokines and adhesion molecules by the endothelial cells represent important features of this dysfunction.

Primary breast cancer therapy in six regions of Germany.

Studies from six regions of Germany (Aachen (W1), Dresden (E1), Jena (E2), Marburg (W2), Munich (W3), and Stuttgart (C1)) have been compared to verify and assess the quality of healthcare using breast cancer as an example. All of the data collection was carried out in comprehensive cancer centres and is population-based, with the exception of C1. Classic prognostic factors and the initial treatment of 8661 women with breast cancer, diagnosed between 1996 and 1998, were examined.

Lethal complications of typhoid-cholera-vaccination. (Case report and review of the literature).

Simultaneous parenteral vaccination against typhoid and cholera lead to death through either anaphylactic shock or endotoxic shock in a 36-year-old male. At autopsy the charactertic features of shock as well as chronic interstitial myocarditis were noted. Moreover, fresh histiocytic and lymphocytic nodules were found in the liver, heart and meninges.

[Histological and biochemical changes in the lung in relation to survival time following femoral fracture in the dog].

Following an experimentally applied fracture of the upper limb fat embolism can be demonstrated in the lungs. By quantitative histological evaluation and biochemical lipid analysis a definite correlation can be observed between the amount of fat in the lungs and the time interval that had elapsed between fracture and death of the animals. More fat is to found in lungs histologically as well as biochemically in those animals, in which the time interval was shorter (165 minutes) than in those which survived for a longer period of time (168 hours).