Publications by authors named "Cezary A Szmigielski"
ECHO-MPS, a dual modality strategy of cardiac imaging to identify myocardial ischemia.
Int J Cardiovasc Imaging
December 2024
Article Synopsis
- The study aimed to assess the effectiveness of combining resting echocardiography (TTE) and stress myocardial perfusion scintigraphy (MPS) for diagnosing coronary artery disease in patients with stable angina and normal left ventricle (LV).
- Researchers hypothesized that a normal LV on TTE could eliminate the need for resting MPS, thus reducing radiation exposure without sacrificing diagnostic accuracy.
- Results showed that the ECHO-MPS approach achieved similar diagnostic accuracy to the standard method, indicating that stress MPS alone may suffice for patients with normal systolic LV function.
Background: Renal artery stenosis (RAS) reflects more widespread atherosclerosis deposition and is associated with high morbidity and mortality. According to the guidelines, a discrepancy in the size of the kidneys of over 15 mm found in an ultrasound should initiate the RAS diagnostic algorithm. This study aims to find the optimal threshold for renal asymmetry that better reflects the frequency of a significantly abnormal renal-aortic ratio (RAR), justifying further RAS diagnostic workup, than the currently used cut-off of 15 mm difference in renal diameters.
View Article and Find Full Text PDFBackground The patients with nonalcoholic fatty liver disease demonstrate an increased cardiovascular risk. The adverse influence of liver abnormalities on cardiac function are among many postulated mechanisms behind this association. The aim of the study was to evaluate cardiac morphology and function in patients with morbid obesity referred for bariatric surgery with liver biopsy.
View Article and Find Full Text PDFUsing the best quality of clinical research evidence is essential for choosing the right treatment for patients. How to identify the best research evidence is, however, difficult. In this narrative review we summarise these threats and describe how to minimise them.
View Article and Find Full Text PDFBackground: The conduct of clinical trials is increasingly challenging due to greater complexity and governance requirements as well as difficulties with recruitment and retention. Electronic Health Records for Clinical Research (EHR4CR) aims at improving the conduct of trials by using existing routinely collected data, but little is known about stakeholder views on data availability, information governance, and acceptable working practices.
Methods: Senior figures in healthcare organisations across Europe were provided with a description of the project and structured interviews were subsequently conducted to elicit their views.