Publications by authors named "Ceylan Balaban"

Article Synopsis
  • Sunlight helps our skin make vitamin D through UVB radiation, but some places don't get enough UVB in winter, which can affect brain health.
  • A study looked at 6,972 people with bipolar I disorder from over 70 countries to see if not getting enough UVB was related to when they first had symptoms.
  • The results suggested that people in areas with less UVB tended to show symptoms of bipolar disorder about 1.66 years earlier, but more research is needed to understand the role of vitamin D and UVB in this condition.
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Objective: Circadian rhythm disruption is commonly observed in bipolar disorder (BD). Daylight is the most powerful signal to entrain the human circadian clock system. This exploratory study investigated if solar insolation at the onset location was associated with the polarity of the first episode of BD I.

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Article Synopsis
  • The study investigates the genetic and phenotypic traits associated with age at onset (AAO) and polarity at onset (PAO) in bipolar disorder to enhance understanding of the illness and develop screening tools.
  • Results indicate that an earlier AAO is linked to more severe symptoms, such as psychosis and suicidality, as well as variations in educational success and living situations.
  • The research reveals a significant relationship between higher polygenic risk scores for other mental disorders and earlier AAO, although no significant associations were found for PAO, highlighting considerable variability across different cohorts.
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The present work investigated the impact of affect in landmark-based wayfinding. We assumed that affect-laden landmarks improve wayfinding performance and have an impact on later landmark recognition. To investigate our hypotheses, we ran two experiments in a virtual maze.

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Depression is a common neuropsychiatric manifestation among Alzheimer's disease (AD) patients. It may compromise everyday activities and lead to a faster cognitive decline as well as worse quality of life. The identification of promising biomarkers may therefore help to timely initiate and improve the treatment of preclinical and clinical states of AD, and to improve the long-term functional outcome.

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