Case report: Exploring Lynch Syndrome through genomic analysis in a mestizo Ecuadorian patient and his brother.

Lynch Syndrome (LS) is a hereditary disorder characterized by genetic mutations in DNA mismatch repair genes, affecting approximately 0.35% of the population. LS primarily increases the risk of colorectal cancer (CRC), as well as various other cancer types like endometrial, breast, and gastric cancers.

Assessment of the COVID-19 pandemic progression in Ecuador through seroprevalence analysis of anti-SARS-CoV-2 IgG/IgM antibodies in blood donors.

Introduction: Coronavirus Disease 2019 (COVID-19) is a severe respiratory illness caused by the RNA virus SARS-CoV-2. Globally, there have been over 759.4 million cases and 6.

Clinical, cytogenetic, and genomic analyses of an Ecuadorian subject with Klinefelter syndrome, recessive hemophilia A, and 1;19 chromosomal translocation: a case report.

Background: Hemophilia A is considered one of the most common severe hereditary disorders. It is an X-linked recessive disease caused by a deficiency or lack of function of the blood clotting factor VIII. Klinefelter syndrome is a genetic disorder that affects male individuals due to one or more extra X chromosomes, present in all cells or with mosaicism.

One-dimensional Luttinger liquids in a two-dimensional moiré lattice.

The Luttinger liquid (LL) model of one-dimensional (1D) electronic systems provides a powerful tool for understanding strongly correlated physics, including phenomena such as spin-charge separation. Substantial theoretical efforts have attempted to extend the LL phenomenology to two dimensions, especially in models of closely packed arrays of 1D quantum wires, each being described as a LL. Such coupled-wire models have been successfully used to construct two-dimensional (2D) anisotropic non-Fermi liquids, quantum Hall states, topological phases and quantum spin liquids.

Landau quantization and highly mobile fermions in an insulator.

In strongly correlated materials, quasiparticle excitations can carry fractional quantum numbers. An intriguing possibility is the formation of fractionalized, charge-neutral fermions-for example, spinons and fermionic excitons-that result in neutral Fermi surfaces and Landau quantization in an insulator. Although previous experiments in quantum spin liquids, topological Kondo insulators and quantum Hall systems have hinted at charge-neutral Fermi surfaces, evidence for their existence remains inconclusive.

Biology and Management of Bacterial Spot of Peppers in Oklahoma.

Bacterial spot, an important disease of bell and chili peppers grown in Oklahoma, is caused by . We evaluated isolates from 1995 to 2015 ( = 72) for avirulence alleles and race by assessing hypersensitive responses (HRs) on differentials with resistance genes , , , or . Most isolates (96%) expressed (races 1, 3, 7, 8), and only three were virulent on (race 6).

Evidence for an edge supercurrent in the Weyl superconductor MoTe.

Edge supercurrents in superconductors have long been an elusive target. Interest in them has reappeared in the context of topological superconductivity. We report evidence for the existence of a robust edge supercurrent in the Weyl superconductor molybdenum ditelluride (MoTe).

A pilot study on the evaluation of eye, head, and trunk coordination in subjects with chronic whiplash during a target-tracking task - A driving context approach.

Background: Motor vehicle accidents (MVA) are the most common causes of whiplash injuries. Difficulties with driving and changes in driving behavior are reported by subjects with chronic whiplash associated disorders (WAD). Proper eye and head coordination is required for driving tasks.

Characterization of the Race Structure of Causing Blackleg of Winter Canola in Oklahoma and Kansas.

Blackleg, caused by the fungus , is a widespread disease of winter canola () in Oklahoma and Kansas. Deployment of genetic resistance is the primary strategy for managing blackleg. Resistance genes () in canola interact with avirulence genes in the fungus () in a gene-for-gene manner.

Triangular Rare-Earth Lattice Materials RbBa R(BO) ( R = Y, Gd-Yb) and Comparison to the KBa R(BO) Analogs.

A previously unreported family of electrically insulating rare-earth borates, RbBa R(BO) ( R = Y, Gd-Yb), was designed and then successfully obtained by traditional solid-state reaction. They crystallize in a monoclinic crystal system space group P2 /m (No. 11).

High-Pressure Synthesis and Characterization of β-GeSe-A Six-Membered-Ring Semiconductor in an Uncommon Boat Conformation.

Two-dimensional materials have significant potential for the development of new devices. Here we report the electronic and structural properties of β-GeSe, a previously unreported polymorph of GeSe, with a unique crystal structure that displays strong two-dimensional structural features. β-GeSe is made at high pressure and temperature and is stable under ambient conditions.

[Khorama score as a predictive tool for thromboembolic events in high risk patients].

Background: There is an established relation between cancer and the development of thromboembolic venous disease. Khorana et al developed a predictive score using clinical characteristics and laboratory values to stratify patients according to their risk.

Aim: To characterize using Khorana score, patients with active cancer and a diagnosis of thromboembolic disease during hospitalization in an oncology hospital.

Endohedral gallide cluster superconductors and superconductivity in ReGa5.

We present transition metal-embedded (T@Gan) endohedral Ga-clusters as a favorable structural motif for superconductivity and develop empirical, molecule-based, electron counting rules that govern the hierarchical architectures that the clusters assume in binary phases. Among the binary T@Gan endohedral cluster systems, Mo8Ga41, Mo6Ga31, Rh2Ga9, and Ir2Ga9 are all previously known superconductors. The well-known exotic superconductor PuCoGa5 and related phases are also members of this endohedral gallide cluster family.

The Impact of Red Light Cameras on Crashes Within Miami-Dade County, Florida.

Objective: To determine the safety effect of red light camera (RLC) programs, this study attempted to estimate its impact on collisions within Miami-Dade County, Florida Methods: A before-after evaluation using a comparison group along with traffic control correction was employed. Twenty signalized intersections with RLCs that began enforcement on January 1, 2011, were matched to 2 comparison sites located at least 2 miles from camera sites to minimize spillover effect. An empirical Bayes analysis was used to account for potential regression to the mean effects.