The evaluation of oxidative stress in patients with chronic renal failure.

Background: Free radical-mediated changes are thought to be involved with atherosclerosis in patients with chronic renal failure.

Methods: The protein carbonyl and malondialdehyde (MDA) levels in serum as the markers of radical-induced protein and lipid oxidations were measured in chronic renal failure patients.

Results: Serum carbonyl and MDA levels in both hemodialysis and peritoneal dialysis patients were not found to be different as compared with healthy subjects.