Publications by authors named "Cetin B"
This study was conducted to reveal the relationship between nursing students' spiritual intelligence levels and their compliance with professional values. This research was designed as a cross-sectional and correlational study. The study included 311 nursing students from a university in Türkiye.
View Article and Find Full Text PDFBackground: S. pneumoniae is widely recognized as a leading cause of respiratory infections worldwide, often resulting in high mortality rates. However, the advent of microfluidic technologies has brought significant advancements, including the simplified, sensitive, cost-effective, and rapid approach to pneumococcal bacteremia detection.
View Article and Find Full Text PDFBackground: The prevalence of meningococcal carriage and serogroup distribution is crucial for assessing the epidemiology of invasive meningococcal disease, forecasting outbreaks and formulating potential immunization strategies. Following the meningococcal carriage studies conducted in Turkey in 2016 and 2018, we planned to re-evaluate meningococcal carriage in children, adolescents and young adults during the COVID-19 pandemic period.
Methods: In the MENINGO-CARR-3 study, we collected nasopharyngeal samples from 1585 participants 0-24 years of age, across 9 different centers in Turkey.
Article Synopsis
- The study evaluates a new meningococcal vaccine (MenABCWY) that combines components of the existing MenB vaccine (4CMenB) and the MenACWY vaccine, aiming to provide broad immunization against various meningococcal strains and ease vaccination schedules.
- Conducted as a phase 3 randomized trial across multiple countries, healthy participants aged 10-25 were assigned to receive different vaccine schedules to assess safety, immune response, and consistency of vaccine lots.
- The trial primarily focused on the immune response to MenB strains, comparing MenABCWY's effectiveness to 4CMenB and evaluating the consistency of immune responses among different production lots of the vaccines.
Article Synopsis
- The study introduced the Explainable Mandibular Third Molar Convolutional Neural Network (E-mTMCNN) to enhance the detection of mandibular third molars in panoramic radiography, aiming to improve clinical decision-making in dentistry.
- A new dataset, the Mandibular Third Molar dataset, was created for the study, incorporating various image preprocessing techniques and demonstrating that the E-mTMCNN, built on GoogLeNet, achieved high performance metrics, including 87.02% classification accuracy.
- The model utilized Local Interpretable Model-Agnostic Explanations (LIME) for transparency in decision-making, and a survey of dental experts showed strong clinical acceptance and reliability of the system.
Application of radiomics features in differential diagnosis of odontogenic cysts.
Dentomaxillofac Radiol
March 2025
Article Synopsis
- The study aimed to differentiate between radicular cysts (RCs), dentigerous cysts (DCs), and odontogenic keratocysts (OKCs) using radiomic features as a non-invasive diagnosis method before surgery.
- A total of 161 cysts were analyzed through semi-automatic segmentation of CBCT images, focusing on various shape-based and textural features to assess their differences.
- Results indicated significant statistical differences in radiomic features among the cyst types, suggesting these features could help with differential diagnosis without needing a biopsy.
Trigeminal neuralgia (TN) is a disease that causes severe pain that can seriously affect the quality of life. This study aimed to compare the effectiveness of two different low-level laser therapies (LLLT) as alternatives to medical treatment to reduce pain and improve the quality of life in patients with TN. A total of 45 patients were randomly divided into 3 groups.
View Article and Find Full Text PDFArticle Synopsis
- Meningococcal serogroup B (MenB) vaccination with the 4CMenB vaccine was tested for its effectiveness and safety among 3,651 healthy participants aged 10 to 25, using different dosing schedules (0-2, 0-6, and 0-2-6 months).
- The study measured the immune response through two methods: a test-based approach showing high immune breadth (over 78%) and a responder-based approach indicating a significant percentage of participants achieved strong responses (up to 93.4% for the 0-2-6 schedule).
- The results showed no major differences in effectiveness across the dosing schedules, confirming that the simpler 2-dose regimen (0-2)
Objectives: Evaluation of the validity of the Quadruple-D score in the prediction of success in pediatric stone disease.
Materials And Methods: Of the 292 children treated with SWL between 2007 and 2023, a total of 158 children who had adequate follow-up data and evaluated with non-contrast computed tomography before SWL, were included in the study. Parameters were calculated for each of the stone volume (SV), skin-to-stone distance (SSD), stone density (SD) and stone location (SL) variables.
Objectives: This study aims to compare the effectiveness of the layered curriculum method (LCM) and project-based learning method (PBLM), on dental students in the evaluation of cysts and tumors affecting the jaws and surrounding tissues, which have an important place in dental practice.
Methods: Forty-nine 3rd-year dental students who agreed to participate in the study voluntarily were randomly divided into two groups: LCM and PBLM. Pre-test was administered to all students.
Article Synopsis
- This study investigates risk factors for all-cause mortality and major cardiovascular events in patients undergoing ambulatory blood pressure monitoring, which helps track blood pressure outside of clinical settings.! -
- The research analyzed data from 1,291 patients, finding that survival rates improved with certain blood pressure patterns and age, while poorer outcomes were associated with smoking and specific blood pressure dips.! -
- The study emphasizes the importance of diastolic blood pressure dipping and nighttime variability in predicting health outcomes, highlighting the need for personalized treatment approaches in hypertension management.!
Article Synopsis
- * A study involving 223 bladder cancer cases found that higher-grade and higher-stage tumors had decreased E-cadherin and increased vimentin expressions, confirming the role of EMT, while galectin-3 levels were higher in early-stage (T1) high-grade tumors but dropped in later stages (T2).
- * The results suggest that galectin-3 is potentially important in early tumor progression, highlighting it as a possible
Aim: This study aimed to determine the changes in the temporomandibular joint due to ethnicity and to reveal gender differences.
Methods: This retrospective study included the evaluation of cone beam computed tomography (CBCT) images of 110 patients (220 temporomandibular joint {TMJs}), 64 dentulous (32 females, 32 males) and 46 edentulous (18 females, 28 males). Anterior, superior, and posterior joint spaces and the roof of the glenoid fossa (GF) were measured in sagittal views.
Although handwriting impairment is a frequent sign of Parkinson's disease (PD), its significance in the evaluation processes of these patients may be overlooked among physicians. Therefore, we would like to report an illustrative patient who presented with isolated micrographia initially; but received the diagnosis of PD in the follow-up.
View Article and Find Full Text PDFArticle Synopsis
- Scientists discovered a new way to study how proteins in the brain can be changed after they're made, specifically focusing on a type called "dopaminylation."
- They found over 1,500 proteins that have this change, many of which are important for sending signals in brain cells and helping with memory.
- One protein, called γCaMKII, plays a big role in helping neurons talk to each other and might be important for learning and adapting to new situations.
Article Synopsis
- - Disruptions in normal development and health conditions often stem from malfunctioning genes, prompting scientific research to focus on replacing or modifying these defective genes for better disease treatment and prevention.
- - Recent advancements in gene and cell therapy, particularly through techniques like CRISPR-Cas, are reshaping our understanding of genetic disorders and leading to new FDA and EMA-approved treatments.
- - This review highlights the evolution of gene editing technologies, examining their potential to transform genetic disease treatment while discussing ethical considerations and regulatory challenges they face.
Following soil disturbances, establishing healthy roadside vegetation can reduce surface water runoff, improve soil quality, decrease erosion, and enhance landscape aesthetics. This study explores the use of organic soil amendments (OAs) as alternatives to conventional vegetation growth approaches, aiming to provide optimal compost mixing ratios for poor soils, and clarify guidelines for OAs' use in roadside projects. Three sandy loam soils and one loam soil were chosen for the study.
View Article and Find Full Text PDFPost-polio syndrome (PPS) affects former polio patients, manifesting decades after initial infection with progressive symptoms like pain, fatigue, and muscle weakness. Diagnosis relies on the clinical criteria and exclusion of other probable causes. The purpose of this study is to determine the scope and new diagnostic value of magnetic resonance imaging (MRI) in identifying muscle involvement in PPS and distinguishing it from prior poliomyelitis (PPM).
View Article and Find Full Text PDFHerein, we present the case of a 57-year-old male patient who was admitted to our center due to progressive writing difficulty and slowness of his right hand over the last 3 years. In conclusion of the clinical and laboratory workup, a diagnosis of multiple system atrophy (MSA) was established. Our report on progressive micrographia (PM) constitutes a crucial sample remarking on this intriguing manifestation in another disease subtype of MSA, which differs from Parkinson's disease in terms of the clinical and pathophysiological processes.
View Article and Find Full Text PDFBackground: Data on antifungal prescribing in neonatal patients are limited to either single-center or single-country studies or to 1-day recording. Therefore, we assessed antifungal longitudinal usage in neonatal units (NUs) within Europe.
Methods: CALYPSO, a prospective weekly point prevalence study on antifungal drug usage in NUs in 18 hospitals (8 European countries), was conducted in 2020 during a 12-week period.
Article Synopsis
- * Patients undergoing surgery for DDH were grouped based on different factors like age and family history, with the research focusing on the histological features and the presence of specific proteins (MMP-2, MMP-9, and ADAMTS-7).
- * Findings show that the ligamentum teres has signs of moderate inflammation and other changes, and that the levels of MMP-2, MMP-9, and ADAMTS-7 are positively linked to these tissue changes
Article Synopsis
- The study compared the effectiveness of local massage, corticosteroid injections, and extracorporeal shock wave therapy (ESWT) on patients with lateral epicondylitis (LE).
- 52 patients were randomly assigned to one of the three treatment groups and assessed using various clinical scoring systems at multiple follow-up points over six months.
- Results indicated that ESWT provided the best long-term outcomes, while corticosteroid injections showed worsening effects over time, suggesting a need for further research on combined treatment approaches.
One significant constraint in the advancement of biosensors is the signal-to-noise ratio, which is adversely affected by the presence of interfering factors such as blood in the sample matrix. In the present investigation, a specific aptamer binding was chosen for its affinity, while exhibiting no binding affinity towards non-target bacterial cells. This selective binding property was leveraged to facilitate the production of magnetic microparticles decorated with aptamers.
View Article and Find Full Text PDF