Publications by authors named "Cesar Minguez Ojeda"

Article Synopsis
  • This study assesses the outcomes of adrenalectomy for pheochromocytoma in obese versus nonobese patients, using data from 46 centers from 2012 to 2022.
  • It finds that while obesity does not significantly increase the rate of complications or comprehensive complication index (CCI), it does lead to a longer hospital stay for patients.
  • Furthermore, minimally invasive surgical techniques, like laparoscopic and robotic surgeries, are associated with less morbidity in obese patients, and a retroperitoneal approach may provide additional benefits.
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  • The study aimed to analyze changes in kidney function after radical cystectomy (RC) and identify factors causing these changes to improve early detection and tailored strategies for patient management.
  • A retrospective analysis of 316 patients who underwent RC from 2010 to 2019 was conducted, utilizing a competing risk Cox model to identify long-term chronic kidney disease (CKD) predictors.
  • Results showed that 43.7% of patients developed CKD within five years, with factors such as hypertension, prior hydronephrosis, acute kidney injury, and urinary tract infections increasing the risk; protective factors included a pre-surgery high eGFR.
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Background: Malignant ureteral obstruction (MUO) is a common condition that complicates the course of advanced malignancies. The aims of this study are to analyze the causes, management, and survival of patients with obstructive nephropathy due to malignant ureteric obstruction and to determine prognostic factors. Furthermore, we studied the complications and outcomes in patients who underwent urinary diversion.

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  • This study examines the surgical outcomes and predictive factors for long-term survival in patients who underwent surgery for adrenal metastasis at two Spanish hospitals from 2005 to 2021.
  • A total of 33 patients participated, with most undergoing laparoscopic surgery; the majority had lung or kidney tumors, and synchronous metastasis was linked to a higher risk of complications.
  • Results showed that the average progression-free survival was 7.5 months, and disease-specific survival was 22.5 months, with lower survival rates seen in patients with lung cancer compared to those with other types.
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  • The study aimed to assess how obesity and overweight affect surgical outcomes in patients undergoing adrenalectomy for adrenal tumors from 2010 to 2022.
  • Results indicated that 9.6% of patients were obese, 54.8% were overweight, and obesity correlated with higher blood pressure, dyslipidemia, and more bilateral tumors compared to non-obese patients.
  • Although overall complication rates were similar, obese patients faced significantly more postoperative complications and longer hospital stays, with obesity identified as a primary independent risk factor.
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Seminal vesicles can be affected by tumours originating in other locations. However, primary tumours of the seminal vesicle are extremely rare, with less than 100 cases reported in literature. Seminal vesicle adenocarcinoma is the most common type, but there are also other malign lesions.

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Background: The coronavirus disease 2019 (COVID-19) pandemic has affected care for diseases like cancer. The aim was to evaluate the impact of COVID-19 on waiting times for diagnosis and treatment of prostate cancer (PC), as well as the possible effect on the treatment results in PC patients undergoing radical prostatectomy.

Methods: We compared the results of 497 patients who underwent biopsy prior to the COVID-19 pandemic (1 January-31 December 2019) with those of 290 patients biopsied during the COVID-19 pandemic (1 January-31 December 2020).

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Article Synopsis
  • The study compares cardiometabolic health outcomes in patients with nonfunctioning adrenal incidentalomas (NFAI) and autonomous cortisol secretion (ACS) who either underwent adrenal surgery or were managed without surgery.
  • It analyzed 486 NFAI patients (16 surgical, 470 conservative) and 259 ACS patients (42 surgical, 217 conservative) from January 2011 to October 2020, noting that ACS patients had higher hypertension and glucose levels at baseline compared to NFAI patients.
  • Results showed that ACS patients who had surgery experienced significantly greater reductions in glucose and triglyceride levels, while NFAI patients also saw improved blood pressure control post-surgery, indicating adrenalectomy benefits extend beyond just ACS cases.
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The purpose of our study was to develop a predictive model to rule out pheochromocytoma among adrenal tumours, based on unenhanced computed tomography (CT) and/or magnetic resonance imaging (MRI) features. We performed a retrospective multicentre study of 1131 patients presenting with adrenal lesions including 163 subjects with histological confirmation of pheochromocytoma (PHEO), and 968 patients showing no clinical suspicion of pheochromocytoma in whom plasma and/or urinary metanephrines and/or catecholamines were within reference ranges (non-PHEO). We found that tumour size was significantly larger in PHEO than non-PHEO lesions (44.

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  • The study investigated presurgical and surgical risk factors linked to intraoperative complications in patients with pheochromocytomas from ten Spanish hospitals between 2011 and 2021, involving 162 surgeries on 159 patients.
  • Findings revealed that 33.3% of the patients experienced intraoperative complications, with hypertensive crises being the most common, followed by prolonged hypotension and hemodynamic instability.
  • Factors increasing the risk of complications included higher levels of urine metanephrine and normetanephrine, larger tumor sizes, uncontrolled blood pressure before surgery, pre-treatment with doxazosin, and the absence of perioperative hydrocortisone treatment.
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