Publications by authors named "Cesar Fernandez de-Las-Penas"

: The dry needling of the piriformis muscle (especially in the medial region) is a challenging procedure since there is a high risk of accidentally puncturing the sciatic nerve. This study aimed to explain the variance of the deep limit of the piriformis based on anthropometric and demographic predictors potentially associated with it by exploring if clinicians can select the optimal needle length needed accurately to avoid accidental punctures of the sciatic nerve during palpation-guided dry needling interventions. : An observational study was conducted that included fifty-six patients with piriformis muscle syndrome.

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  • * A national survey of 422 physical therapists in Spain revealed that most had limited training and experience in DN, with common adverse events being post-needling soreness and bent needles.
  • * The study underscores the need for better training on anatomical knowledge and safety protocols, as higher training hours correlated with increased reported complications, indicating gaps in current practice.
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Backgrounds: We aim to evaluate changes in pressure pain sensitivity before and after cardiac surgery using topographical sensitivity maps utilizing a pressure algometer.

Methods: Pressure pain thresholds over 17 thoracic points and 4 distant pain-free points were assessed in 70 patients (women: 29, age: 67.5 years), before and at 1, 3, and 7 postoperative days.

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The aim of the current study was to determine the capability of neurocognitive variables and executive functions to differentiate women with and without fibromyalgia syndrome (FMS). A secondary diagnostic accuracy analysis was conducted. A battery of neurocognitive and executive function tests (the D2 Attention test, the Rey-Osterrieth Complex Figure for visual perception, "Digits D/R/I" tests of the WAIS-IV battery for working memory, the 5-Digit test for mental inhibition, the Symbol Search for processing speed, and the Zoo Test for planning/decision-making) were collected in 129 women with FMS and 111 without FMS.

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  • The study aimed to compare various ultrasound and elastography metrics to distinguish individuals with chronic neck pain from asymptomatic controls.
  • It involved 316 participants, collecting data on demographics, pain levels, and ultrasound features of the cervical multifidus muscle.
  • The key finding was that fatty infiltration in the muscle effectively differentiated those with chronic neck pain, with significant results indicating higher levels in this group compared to controls.
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The aim of this study was to investigate the influence of executive functioning and cognitive performance on individual experimentally induced pain perception during distractor tasks in an asymptomatic pain-free population. A total of 59 healthy pain-free subjects (59.3% women, mean age: 46.

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Objective: To describe the perspectives of a group of COPD patients during the first outbreak of the COVID-19 pandemic and narrate the emotions and polarity (acceptance-rejection) regarding living with COPD during the pandemic.

Design/methods: We used a novel application of lemmatization and thematic analysis of participants' narratives. A study was carried out with eight patients with moderate-severe-very severe COPD during the first outbreak of COVID-19 using purposive sampling.

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Patients with interstitial lung disease (ILD) represent a vulnerable population against an acute SARS-CoV-2 infection. It has been observed that up to 80% of patients with ILD can develop post-COVID-19 symptomatology one year after. This secondary analysis aimed to, 1, compare serological biomarkers before and after surpassing a SARS-CoV-2 infection in individuals with interstitial lung disease (ILD) and, 2, to compare serological biomarkers between ILD patients who develop and those who do not develop post-COVID-19 symptoms.

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The aim of this study was to quantify the multivariate relationships between clinical, cognitive performance, executive functioning, and psychological outcomes in women with fibromyalgia (FMS) using network analyses. Demographic (age, height, weight), clinical (pain history, pain intensity, and related disability), neurocognitive (D2 Attention test, Rey-Osterrieth Complex Figure for visual perception, "Digits D/R/I" tests of the WAIS-IV battery for working memory, the 5-Digit Test for mental inhibition, the Symbol Search for processing speed and the Zoo Test for planning/decision making) and psychological (depressive symptoms, anxiety levels, sleep quality, pain hypervigilance) variables were collected in 129 women with FMS and 111 healthy women. Network analyses were conducted separately for each group to quantify the adjusted correlations between the modeled variables and to assess their centrality indices (i.

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  • The study investigates the role of DNA methylation changes in individuals who developed long-lasting post-COVID pain after being hospitalized for COVID-19 compared to those who did not develop such symptoms.
  • Researchers analyzed saliva samples from 279 COVID-19 survivors, noting that 39.1% of them reported experiencing persistent pain, particularly localized pain and headaches.
  • The results revealed no significant differences in DNA methylation levels associated with the angiotensin-converting enzyme 2 promoter between those with and without post-COVID pain, suggesting methylation may not be a key factor in the development of long-lasting symptoms.
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It is known that SARS-CoV-2 can translocate via membrane ACE2 exopeptidase into the host cells, and thus hypomethylation of ACE2 possibly upregulates its expression, enhancing the risk of SARS-CoV-2 infection. This study investigated if DNA methylation levels of the ACE2 promoter are associated with the development of post-COVID-19 symptomatology in a cohort of COVID-19 survivors who had been previously hospitalized. Non-stimulated saliva samples were obtained from 279 (51.

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Objective: The long-lasting persistence of autoantibodies stands as one of the hypotheses explaining the multisystemic manifestations seen in individuals with post-COVID-19 condition. The current review offers restricted insights into the persistence of autoantibodies in plasma/serum in people with post-COVID symptoms.

Methods: PubMed/MEDLINE, CINAHL, EMBASE, and Web of Science databases, as well as on medRxiv and bioRxiv preprint servers were searched up to January 5, 2024.

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  • The study evaluated the reliability of measuring supraspinatus tendon (SST) thickness in 30 adolescent swimmers, split between those with SST tendinopathy and a control group, using various measurement procedures.
  • It found that SST thickness was significantly greater in swimmers with tendinopathy compared to controls across all measurement methods.
  • The most reliable measurement method was determined to be one that involved using references at 10, 15, and 20 mm from the biceps tendon, demonstrating strong reliability scores and a low error rate.
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  • The study examined how administering Remdesivir during the acute phase of COVID-19 affects the development of post-COVID symptoms in hospitalized survivors.
  • It involved a case-control format, comparing 216 survivors who received Remdesivir with 216 who didn't, while controlling for age, sex, BMI, and vaccination status.
  • Findings indicated that receiving Remdesivir acted as a protective factor against long-term post-COVID symptoms like fatigue, pain, and memory loss, suggesting its potential benefits for previously hospitalized COVID-19 patients.
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The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pathogen provoked the most unprecedented sanitary outbreak of the current century by causing coronavirus disease 2019 (COVID-19), which has led to approximately 775 million confirmed cases and more than 7 million deaths globally [...

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  • Myofascial trigger points (TrPs) are sensitive spots in muscles that cause both local and referred pain; this study explores their role in patients with cervical dystonia (CD).
  • A total of 31 participants were assessed for TrPs in specific neck and shoulder muscles, and pain levels were documented using the Toronto Western Spasmodic Torticollis Rating Scale.
  • The study found that only patients with pain had active TrPs, while all patients had latent TrPs, suggesting that active TrPs may contribute to pain and disability in CD.
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Percutaneous electrical nerve stimulation (PENS) appears to be effective for the treatment of musculoskeletal pain. The aim of this trial was to investigate the effects on disability and pain, as well as on the psychological aspects of adding PENS into an exercise program in patients with subacromial pain syndrome. A randomized, parallel-group clinical trial was conducted.

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The purpose of this study was to compare the effects of dry needling (DN) intervention on the responses of muscle tone, stiffness, and elasticity, as well as power, pressure pain thresholds, and blood perfusion of the flexor carpi radialis muscle in mixed martial arts (MMA) athletes. Thirty-two trained/developmental men MMA fighters (25.5±4.

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  • This study aimed to explore the existence of widespread pain sensitivity (hyperalgesia) and structural changes in wrist tendons and muscles in individuals with lateral epicondylalgia (LE).
  • Thirty-seven LE patients, along with 37 pain-free controls, were assessed for pressure pain thresholds and underwent ultrasound evaluations to measure changes in tendon and muscle structure.
  • Results showed that LE patients had significantly lower pain thresholds and notable structural changes in the wrist extensor tendon compared to controls, but these changes were unrelated to each other in terms of pain sensitivity.
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This population-based study investigated the prevalence of de novo, multitype, post-coronavirus disease (COVID) pain and its associated risk factors in previously hospitalized coronavirus disease 2019 (COVID-19) survivors. The nationwide, cross-sectional study included a cohort of Danish residents previously hospitalized due to severe acute respiratory syndrome coronavirus-2 infection between March 2020 and December 2021. Demographic data, preexisting medical comorbidities, previous pain-related symptoms, medication use for pain management, pain intensity (4-point scale), and development of de novo, multitype, post-COVID pain were collected by a self-reported survey distributed via e-Boks (a secured national digital mail system used in Denmark to provide public information to residents).

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Patients with fibromyalgia syndrome tend to report deficits in cognitive functions; however, there is no clear consensus on which cognitive domains are impaired. The aim of this study was to compare the differences in cognitive performance between a group of patients with fibromyalgia syndrome and a group of pain-free subjects controlling for the covariables anxiety, depression, and sleep quality. In total, 130 patients with fibromyalgia syndrome and 111 pain-free subjects with an average age of 54.

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